Nitrous Oxide inhalation among adolescents: prevalence, correlates, and co-occurrence with volatile solvent inhalation
. J Psychoactive Drugs 2009;41:337-47.
In some applications, nonvolatile solvents are acceptable, leading to significant "green" advantages including nonflammability, no solvent emissions to the atmosphere, no contribution to smog formation, and lack of human exposure through solvent inhalation
. However, if nonvolatile solvents are to be used as reaction media, then a mechanism by which the product can be removed from the solvent must be identified.