softening

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malacia

 [mal-la´she-ah]
softening of a part or tissue related to a disease or other abnormal condition.
tracheal malacia tracheomalacia.

softening

(sof'en-ing)
The process of becoming soft. Synonym: malacia

softening of bones

Osteomalacia.

softening of brain

See: encephalomalacia

white softening

The stage of softening of tissue in which the affected area has become white and anemic.
References in classic literature ?
He had spoken to Rachael only last night, it was true, and had walked with her a little way; but he had his new misfortune on him, in which no one else could give him a moment's relief, and, for the sake of it, and because he knew himself to want that softening of his anger which no voice but hers could effect, he felt he might so far disregard what she had said as to wait for her again.
It belonged in the list of softening, sensuous influences peculiar to this home of Eastern luxury.
'If you ask me Why,' said Mr Meagles, a little disturbed by the question, for he was far more intent on softening her case than the family's, 'I can only refer you to what I have just repeated as having been pretty near my words to Mother.
This might be pride, but was so like humility, that it produced all the softening influence of the latter quality on the public mind.