sodium pump


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pump

 [pump]
1. an apparatus for drawing or forcing liquid or gas.
2. to draw or force liquids or gases.
blood pump a machine used to propel blood through the tubing of extracorporeal circulation devices.
breast pump a pump for taking milk from the breast.
calcium pump the mechanism of active transport of calcium (Ca2+) across a membrane, as of the sarcoplasmic reticulum of muscle cells, against a concentration gradient; the mechanism is driven by hydrolysis of ATP.
enteral feeding pump an infusion pump specifically designed for administration of a solution through a feeding tube.
insulin pump see insulin pump.
intra-aortic balloon pump see intra-aortic balloon pump.
muscle pump compression of veins by the contraction of skeletal muscles, forcing blood towards the heart against the flow of gravity; seen particularly in the deep veins of the lower limbs. Called also venous pump.
proton pump a system for transporting protons across cell membranes, often exchanging them for other positively charged ions.
sodium pump (sodium-potassium pump) the mechanism of active transport driven by the energy generated by Na+,K+-ATPase, by which sodium (Na+) is extruded from a cell and potassium (K+) is brought in, so as to maintain the low concentration of sodium and the high concentration of potassium within the cell with respect to the surrounding medium. A high concentration of intracellular potassium is necessary for vital processes such as protein biosynthesis, certain enzyme activities, and maintenance of the membrane potential of excitable cells. Called also Na+-K+ pump.
stomach pump see stomach pump.
venous pump muscle pump.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

so·di·um pump

a biologic mechanism that uses metabolic energy from ATP to achieve active transport of sodium across a membrane; sodium pumps expel sodium from most cells of the body, sometimes coupled with the transport of other substances, and also serve to move sodium across multicellular membranes such as renal tubule walls.
Farlex Partner Medical Dictionary © Farlex 2012

so·di·um pump

(sō'dē-ŭm pŭmp)
A biologic mechanism that uses metabolic energy from adenosine triphosphate to achieve active transport of sodium across a membrane; sodium pumps expel sodium from most cells of the body, sometimes coupled with the transport of other substances, and also serve to move sodium across multicellular membranes such as renal tubule walls.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

sodium pump

the mechanism by which sodium is removed from inside a cell. When occurring in the axon of a neurone, the pump helps to establish the RESTING POTENTIAL. It is also involved in the transfer of salt in the LOOP OF HENLE. The process requires energy from respiration and is an active process; the energy is derived from breaking down ATP. Sodium pumps occur in all cells and should, perhaps, be referred to as sodium/potassium pumps, because potassium ions move into the cell as sodium ions move out. However, cell membranes are more permeable to potassium ions than to sodium ions, so the former diffuse out faster than sodium diffuses in and sodium is also pumped out faster than potassium is pumped in. This, together with the mobility of large negative organic ions to move out of the axon, maintains the resting potential.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

so·di·um pump

(sō'dē-ŭm pŭmp)
Biologic mechanism that uses metabolic energy from adenosine triphosphate to achieve active transport of sodium across a membrane.
Medical Dictionary for the Dental Professions © Farlex 2012
References in periodicals archive ?
Functional reconstitution of the sodium pump. Kinetics of exchange reaction permormed by reconstituted Na, K-ATPase.
purpuratus was paralleled by a concomitant increase in the total activity of the sodium pump (Fig.
Endogenous sodium pump inhibition: current status and therapeutic opportunities.
An endogenous bufadienolide inhibitor of sodium pump, marinobufagenin, has also been shown to be increased in HF, and its plasma concentrations seem to correlate with severity of disease (65).
For years scientists suspected that chloride cells used their sodium pumps to rid the body of excess sodium ions.
Chromatographygrade C[H.sub.3]CN was obtained from Aldrich Co.; 5-sulfosalicylic acid, CaC[O.sub.3], ouabain, dihydroouabain, porcine cerebral cortex, all reagents for catalytic inhibition of the sodium pump [ATP, ammonium molybdate, Tween 80, and bovine serum albumin (BSA)] as well as goat antirabbit horseradish peroxidase conjugate, phosphate-buffered saline (PBS)-Tween (pH 7.4), and antibodies to progesterone were purchased from Sigma.
Bovine adrenals contain in addition to ouabain, a second inhibitor of the sodium pump. J Biol Chem 1998;273:784-92.
Those findings strongly support the concept of differential regulation of the sodium pump genes.
Reversal of sodium pump inhibitor induced vascular smooth muscle contraction with digibind.
Early data suggested that the unidentified hormone slowed the activity of cellular sodium pumps -- membrane proteins that help transport sodium out of cells.