fluorescein

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fluorescein

 [floo͡-res´ēn]
a fluorescing dye; the sodium salt is used as a contrast medium in retinal angiography and as a diagnostic aid for revealing corneal lesions and fitting contact lenses.

fluor·es·ce·in

(flōr-es'ē-in), [C.I. 45350]
An orange-red crystalline powder that yields a bright green fluorescence in solution and is reduced to fluorescin; a nontoxic, water-soluble indicator used diagnostically to trace water flow.

fluorescein

(flo͝o-rĕs′ē-ĭn, flô-, flō-)
n.
An orange-red compound, C20H12O5, that exhibits intense fluorescence in alkaline solution and is used in medicine for diagnostic purposes, in oceanography as a tracer, and as a textile dye.

fluor·es·ce·in

(flōr-es'ē-in)
[C.I. 45350] An orange-red crystalline powder that yields a bright green fluorescence in solution, and is reduced to fluorescin; a nontoxic, water-soluble indicator used diagnostically to trace water flow and to visualize corneal abrasions or ulcers.

fluorescein

A green dye that fluoresces bright yellow in blue or ultraviolet light. It is used to tag (label) and thus show up ANTIBODIES in tissues. It is also much used by eye specialists (ophthalmologists) to show up ulcers on the cornea and to delineate for photography the blood vessels of the retina. For the latter purpose, the due is injected rapidly into the bloodstream (fluorescein angiography). The drug is on the WHO official list. Brand names are fluorescein, Minims fluorescein, Minims lignocaine (lidocaine, a local anaesthetic) and fluorescein, and Minims proxymetacaine (a local anaesthetic) and fluorescein.

Fluorescein

A brand name for FLUORESCEIN.

Fluorescein

A fluorescent chemical used to examine the cornea.
Mentioned in: Corneal Ulcers

fluorescein

A fluorescent, weak dibasic acid with a molecular weight of 376 whose sodium salt is used in dilute solution as a dye in the fitting of contact lenses, in the detection of corneal abrasions, etc. It is a yellowish-red compound, which fluoresces a brilliant yellow-green under ultraviolet or blue illumination (Fig. F7). Syn. sodium fluorescein. See fluorexon; Burton lamp; Wood's light; rose bengal; staining; break-up time test; fluorescein test.
Fig. F7 Fluorescein on the corneal surface staining A, an abraded area, and B, some damaged epithelial cellsenlarge picture
Fig. F7 Fluorescein on the corneal surface staining A, an abraded area, and B, some damaged epithelial cells

fluor·es·ce·in

(flōr-es'ē-in)
Nontoxic, water-soluble indicator used diagnostically to trace water flow and visualize corneal abrasions.
References in periodicals archive ?
Intravenous sodium fluorescein and 10% dextrose as bladder distention media can both safely be used to visualize ureteral efflux and result in high surgeon satisfaction.
Table: Rate of gross total resection of malignant glioma using sodium fluorescein, in chronological order.
Abbreviations: 16HBE14o-, bronchial epithelial derived cell line; A549, adenocarcinoma-derived epithelial cell line; ALI, air liquid interface; ATI, alveolar type I cells; ATII, alveolar type II cells; EDTA, ethylenediaminetetraacetic acid; hAELVi, human alveolar epithelial lentivirus immortalized cells; LCC, liquid-covered conditions; NCI-H441, epithelial cell line; NaFlu, sodium fluorescein; NP, nanoparticles; TEER, transepithelial electrical resistance; THP-1, monocyte-derived macrophage-like cells
Intravenous sodium fluorescein is routinely used in ophthalmology in retinal angiography, at a dosage of 5 mL of 10% fluorescein, he said.
After 4 hr, the green fluorescence is sighted more significantly in cells that are incubated with sodium fluorescein loaded in RC-albumin nanoparticles than nontargeted chitosan-albumin nanoparticles, and there is no significant fluorescence in cells that are incubated with solution of sodium fluorescein.
Briefly, animals were injected IP with 200 [micro]L 10% sodium fluorescein that was allowed to circulate for 15 min, and blood was collected via cardiac puncture.
Specifically preserved aliquots of the fluid must be obtained in the following manner: (1) heparinized for culture, (2) EDTA for microscopy, (3) sodium fluorescein (NaF) for glucose and lactate, and (4) untreated for further biochemical testing.
One hundred grams of sodium fluorescein were added to the 100-[m.sup.3] tanks for non-drinking water ([10.sup.-3] g/L), and passage of colored water to the drinking water pipe system was monitored at 7 supply points by on-the-spot and laboratory spectrophotometric measurements.
Some studies suggest that the use of high doses of sodium fluorescein is a useful agent intraoperative even without using equipment for visualizacion (28).
There was a significant difference in surgeon satisfaction with the use of mannitol as a bladder distention medium during intraoperative cystoscopy compared with normal saline infusion, oral phenazopyridine, or intravenous sodium fluorescein in an unblinded randomized trial of 130 women who underwent gynecologic surgery at a single institution.

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