blocker

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blocker

 [blok´er]
something that blocks or obstructs a passage or activity; see also antagonist and blocking agent.
β-blocker (beta-blocker) beta-adrenergic blocking agent.
calcium channel blocker calcium channel blocking agent.
potassium channel blocker potassium channel blocking agent.
sodium channel blocker sodium channel blocking agent.

block·er

(blok'er),
An instrument used to obstruct a passage.

blocker

/block·er/ (blok´er) something that blocks or obstructs passage, activity, etc.
α-blocker  alpha-adrenergic blocking agent; see adrenergic blocking agent.
β-blocker  beta-adrenergic blocking agent; see adrenergic blocking agent.
calcium channel blocker  calcium channel blocking agent.
potassium channel blocker  potassium channel blocking agent.
sodium channel blocker  sodium channel blocking agent.

blocker

blocker

A popular term for anything which physically (e.g., a bed blocker, see there) or pharmacologically (e.g., a beta-blocker) impedes a process or activity.

block·er

(blok'ĕr)
1. An instrument used to obstruct a passage.

blocker

something that blocks or obstructs passage, activity, etc.

α-blocker, alpha-blocker
a drug that induces adrenergic blockade at α-adrenergic receptors.
β-blocker, beta-blocker
a drug that induces adrenergic blockade at either β1- or β2-adrenergic receptors, or both (see also beta-blocker).
calcium channel blocker
a drug that selectively inhibits the influx of calcium ions through a specific ion channel of cardiac muscle and smooth muscle cells (see also calcium channel blocker).
H2-receptor blocker
a drug, such as cimetidine that inhibits the secretion of gastric acid stimulated by histamine, pentagastrin, food and insulin, and also basal secretion; used in the treatment of peptic ulcer.
References in periodicals archive ?
Spontaneous type 1 ECG, independently of history of syncope, predicted a higher risk in experiencing SCD than a non-diagnostic ECG which converted to coved-type ECG by exposure to sodium channel blockers during a mean follow-up of 24 [+ or -] 32 months.
Cellular basis for the ECG features of the LQT1 form of the long-QT syndrome: effects of [Beta]-adrenergic agonists and antagonists and sodium channel blockers on transmural dispersion of repolarization and torsade de pointes.
The use of sodium channel blockers to treat arrhythmias in cardiac patients demonstrates how marketing efforts can contradict sound medical practice.
The trial was halted because it clearly showed that the three sodium channel blockers being studied (encainide, flecainide, and morizicine) increased mortality--even though they had effectively corrected the arrhythmia.
Building on this work, we are currently pursuing programs at developing N-type and T-type calcium channels and selected sodium channel blockers.
Pipeline candidates fall under major therapeutic classes such as glutamate receptor antagonists, SOD1 protein folding stabilizers, stem cell therapy, Sodium channel blockers, Interleukin-2 (IL-2) inhibitors, immunomodulators, dopamine antagonists, cell protectants, antioxidants, antibiotics and free radical scavengers.
Detailed information on the use of specific drug classes including tricyclic antidepressants, SSRIs, SNRIs, anticonvulsants, sodium channel blockers, opioids, NSAIDS, cannabinoids and Capsaicin
Chapter 17 Neuropathic Pain Treatments and Prescribing Practices - Sodium Channel Blockers
Many drugs on the market today act on ion channels, either directly or indirectly, including calcium channel blockers for hypertension and angina, and sodium channel blockers for pain.
Drug classes used: For example, tricyclic antidepressants, selective serotonin reuptake inhibitors (SSRIs), serotonin-noradrenalin reuptake inhibitors (SNRIs), anticonvulsants, sodium channel blockers, opioids, non-steroidal anti-inflammatory drugs, cannabinoids, Capsaicin and others
Chapter 12 - Sodium Channel Blockers Late-Stage Drug Analysis
Sodium channel blockers are contraindicated in patients with coronary artery or structural heart disease, potassium channel blockers can predispose patients to dangerous ventricular arrhythmias and mixed ion channel blockers such as amiodarone can be associated with multi-organ toxicity as well as ventricular arrhythmias.

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