smouldering myeloma

smouldering myeloma

A slowly progressive myeloma with an average survival of 10 years, which contrasts with untreated (6-month survival) and treated (3- to 5-year survival) myelomas. Indolent myeloma comprises 5% of myelomas and is often detected by routine lab tests for unrelated reasons; most patients have stage-I disease.
References in periodicals archive ?
Additional studies are ongoing or planned to assess its potential in other malignant and pre-malignant haematologic diseases in which CD38 is expressed, such as smouldering myeloma.
Currently, five Phase III clinical studies with daratumumab in relapsed and frontline multiple myeloma settings are ongoing and additional studies are ongoing or planned to assess its potential in other malignant and pre-malignant diseases on which CD38 is expressed, such as smouldering myeloma, NKT-cell lymphoma, amyloidosis, myelodysplastic syndromes and solid tumours.
They recommend mandatory PET-CT to confirm suspected solitary plasmacytoma, if whole body MRI is unavailable, and to distinguish active from smouldering myeloma if skeletal survey is negative and whole body MRI is not possible.
She has smouldering myeloma, an early form of the condition, which usually progresses to active myeloma, but at a slow rate.
Patients with monoclonal gammopathy of undetermined significance [15] and smouldering myeloma were excluded from the study [16].
Five Phase III clinical studies with daratumumab in relapsed and frontline multiple myeloma settings are currently ongoing, and additional studies are ongoing or planned to assess its potential in other malignant and pre-malignant diseases on which CD38 is expressed, such as smouldering myeloma, NK/T-cell lymphoma, amyloidosis, myelodysplastic syndromes and solid tumours.