smouldering myeloma

A slowly progressive myeloma with an average survival of 10 years, which contrasts with untreated (6-month survival) and treated (3- to 5-year survival) myelomas. Indolent myeloma comprises 5% of myelomas and is often detected by routine lab tests for unrelated reasons; most patients have stage-I disease.

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Additional studies are ongoing or planned to assess its potential for a solid tumour indication and in other malignant and pre-malignant diseases in which CD38 is expressed, such as smouldering myeloma.

Janssen Seeks Expanded Use of Darzalex from EMA in Newly Diagnosed Multiple Myeloma

Currently, five Phase III clinical studies with daratumumab in relapsed and frontline multiple myeloma settings are ongoing and additional studies are ongoing or planned to assess its potential in other malignant and pre-malignant diseases on which CD38 is expressed, such as smouldering myeloma, NKT-cell lymphoma, amyloidosis, myelodysplastic syndromes and solid tumours.

Genmab receives approval for DARZALEX for relapsed or refractory multiple myeloma in Japan

She has smouldering myeloma, an early form of the condition, which usually progresses to active myeloma, but at a slow rate.

'I thought it was arthritis, then I was told I had cancer'

Patients with monoclonal gammopathy of undetermined significance [15] and smouldering myeloma were excluded from the study [16].

Treatment of multiple myeloma in elderly people: long-term results in 178 patients

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