a specimen for microscopic study, the material being spread thinly and unevenly across the slide with a swab or loop, or with the edge of another slide.
Smears from opaque thick liquids or semisolids, such as stool, can be made using a swab to sample and smear the material. From Mahon and Manuselis, 1995.
A thin specimen for examination; it is usually prepared by spreading material uniformly onto a glass slide, fixing it, and staining it before examination.
Biology A sample, as of blood or bacterial cells, spread on a slide for microscopic examination or on the surface of a culture medium.
smear Tuberculosis A specimen gobbed on a glass slide, stained, washed in an acid solution, and examined by LM to detect AFB in a specimen. See Acid-fast bacilli, Wet mount.
A thin specimen for microscopic examination; usually prepared by spreading liquid or semisolid material uniformly onto a glass slide, fixing it, and staining it before examination.
smear (smer) [Old English. smerian, to anoint]
1. In bacteriology, material spread on a surface, as a microscopic slide or a culture medium.
2. Material obtained from infected matter spread over solid culture media.
3. Cellular material obtained from a body structure by swabbing, gently scraping, or scratching.
PREPARATION OF BLOOD SMEAR
PREPARATION OF BLOOD SMEAR
A drop of (anticoagulated) whole blood spread thinly on a glass microscope slide so that blood cell types can be examined, counted, and characterized. Synonym: peripheral blood smear
Procedure: The slide must be grease-free. It is cleaned with alcohol, rinsed in warm water, and wiped clean with a lint-free towel or lens paper.A small drop of blood is placed on the slide; the end of another slide (spreader slide) is placed against the first slide at a 45° angle and pulled back against the drop of blood so that the drop spreads between the point of contact of the two slides. Then the spreader slide is pushed forward against the first slide; the blood will form an even, thin smear. The slide is dried by waving it in the air; it should not be heated. The blood smear is covered with Wright's stain and allowed to stand 2 min. An equal amount of distilled water or buffer solution is added and mixed uniformly. It is allowed to stand 5 min. The stain is gently washed off and the slide is allowed to dry.
A sample of cells taken from the mucosa lining the cheek for chromosomal or other studies.
Pap smearPapanicolaou test.
peripheral blood smear Synonym: blood smear
smear A thin film of tissue, cells, blood or other material spread on a transparent slide for microscopic examination.
A specimen prepared for microscopic study by spreading the material across a slide and treating it with a specific stain.
Thin specimen for examination; usually prepared by spreading material uniformly onto a glass slide, fixing it, and staining it before examination.