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a specimen for microscopic study, the material being spread thinly and unevenly across the slide with a swab or loop, or with the edge of another slide.
Smears from opaque thick liquids or semisolids, such as stool, can be made using a swab to sample and smear the material. From Mahon and Manuselis, 1995.
Pap smear (Papanicolaou smear) see papanicolaou test.


A thin specimen for examination; it is usually prepared by spreading material uniformly onto a glass slide, fixing it, and staining it before examination.


Biology A sample, as of blood or bacterial cells, spread on a slide for microscopic examination or on the surface of a culture medium.


Tuberculosis A specimen gobbed on a glass slide, stained, washed in an acid solution, and examined by LM to detect AFB in a specimen. See Acid-fast bacilli, Wet mount.


A thin specimen for microscopic examination; usually prepared by spreading liquid or semisolid material uniformly onto a glass slide, fixing it, and staining it before examination.


(smer) [Old English. smerian, to anoint]
1. In bacteriology, material spread on a surface, as a microscopic slide or a culture medium.
2. Material obtained from infected matter spread over solid culture media.
3. Cellular material obtained from a body structure by swabbing, gently scraping, or scratching.
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blood smear

A drop of (anticoagulated) whole blood spread thinly on a glass microscope slide so that blood cell types can be examined, counted, and characterized. Synonym: peripheral blood smear

Procedure: The slide must be grease-free. It is cleaned with alcohol, rinsed in warm water, and wiped clean with a lint-free towel or lens paper.A small drop of blood is placed on the slide; the end of another slide (spreader slide) is placed against the first slide at a 45° angle and pulled back against the drop of blood so that the drop spreads between the point of contact of the two slides. Then the spreader slide is pushed forward against the first slide; the blood will form an even, thin smear. The slide is dried by waving it in the air; it should not be heated. The blood smear is covered with Wright's stain and allowed to stand 2 min. An equal amount of distilled water or buffer solution is added and mixed uniformly. It is allowed to stand 5 min. The stain is gently washed off and the slide is allowed to dry.

See: illustrationillustration

buccal smear

A sample of cells taken from the mucosa lining the cheek for chromosomal or other studies.

Pap smear

Papanicolaou test.

peripheral blood smear

Synonym: blood smear


A thin film of tissue, cells, blood or other material spread on a transparent slide for microscopic examination.


A specimen prepared for microscopic study by spreading the material across a slide and treating it with a specific stain.
Mentioned in: Leprosy


Thin specimen for examination; usually prepared by spreading material uniformly onto a glass slide, fixing it, and staining it before examination.
References in periodicals archive ?
The smear campaign isn't limited to the group; youth activists and revolutionary movements have faced similar accusations, often being called thugs when protesting.
"Some non-Muslim intellectuals are thinking that we Muslims react emotionally to smear campaigns because we don't have the knowledge to confront the critiques rationally," Akbar said while describing his organization's plan to hold a seven-month campaign to highlight the life and teachings of the Prophet.
Jarrah reportedly told Hariri that he and Future bloc were victims of a smear campaign mounted by the Syrian authorities and that pro-Hariris remain totally detached and unconcerned with Syrian domestic issues.
ElBaradei, who won the Nobel Peace Prize in 2005 said that in response to such a "smear campaign", and under such a repressive regime, boycotting the elections, signing petitions, peaceful demonstrations and civil disobedience are the means of change, and "the only means available to us".
"For reasons unbeknownst to us, Mayweather, his father, Floyd Mayweather Sr, his adviser, Leonard Ellerbe and Golden Boy Promotions have decided to engage in a smear campaign against Mr Pacquiao," the group wrote.
is rapidly mounting due to its escalation of the smear campaign to bring down the political system in the DPRK'' a Foreign Ministry spokesman was quoted as saying by the official Korean Central News Agency.
Just before Tucson went to the polls, Kolbe's enemies on the far right launched a smear campaign against him, plastering his district with slanderous posters that said KOLBE RAPED A BOY and KOLBE: I HAVE AIDS.
A British member of Parliament accused his opponents of launching a smear campaign against him in April by alleging that he had taken bribes from Saddam Hussein.
SUPPORTERS have demanded Britain's ambassador to Uzbekistan be returned to his post, after falling victim to a smear campaign.
Now Percy is a Hogwarts graduate and assistant to Minister Fudge, and his blind affection for his masters leads him to join the smear campaign against Harry.
The jury found that six of the seven defendants violated Bari and Cherney's First and Fourth Amendment rights by arresting the activists, conducting searches of their homes, and carrying out a smear campaign in the press, calling Earth First!
THE Plaid Cymru MP who uncovered the Mittal scandal says he has been tipped off that the Labour Party is planning a smear campaign against him.