smear


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smear

 [smēr]
a specimen for microscopic study, the material being spread thinly and unevenly across the slide with a swab or loop, or with the edge of another slide.
Smears from opaque thick liquids or semisolids, such as stool, can be made using a swab to sample and smear the material. From Mahon and Manuselis, 1995.
Pap smear (Papanicolaou smear) see papanicolaou test.

smear

(smēr),
A thin specimen for examination; it is usually prepared by spreading material uniformly onto a glass slide, fixing it, and staining it before examination.

smear

(smēr) a specimen for microscopic study prepared by spreading the material across the slide.
Pap smear , Papanicolaou smear see under test.

smear

(smîr)
n.
Biology A sample, as of blood or bacterial cells, spread on a slide for microscopic examination or on the surface of a culture medium.

smear

Etymology: AS, smeoru, grease
a laboratory specimen for microscopic examination prepared by spreading a thin film of tissue or fluid on a glass slide. A dye, stain, reagent, diluent, or lysing agent may be applied to the specimen, depending on the purpose of the examination.

smear

Tuberculosis A specimen gobbed on a glass slide, stained, washed in an acid solution, and examined by LM to detect AFB in a specimen. See Acid-fast bacilli, Wet mount.

smear

(smēr)
A thin specimen for microscopic examination; usually prepared by spreading liquid or semisolid material uniformly onto a glass slide, fixing it, and staining it before examination.

smear

(smer) [Old English. smerian, to anoint]
1. In bacteriology, material spread on a surface, as a microscopic slide or a culture medium.
2. Material obtained from infected matter spread over solid culture media.
3. Cellular material obtained from a body structure by swabbing, gently scraping, or scratching.
Enlarge picture
PREPARATION OF BLOOD SMEAR
Enlarge picture
PREPARATION OF BLOOD SMEAR

blood smear

A drop of (anticoagulated) whole blood spread thinly on a glass microscope slide so that blood cell types can be examined, counted, and characterized. Synonym: peripheral blood smear

Procedure: The slide must be grease-free. It is cleaned with alcohol, rinsed in warm water, and wiped clean with a lint-free towel or lens paper.A small drop of blood is placed on the slide; the end of another slide (spreader slide) is placed against the first slide at a 45° angle and pulled back against the drop of blood so that the drop spreads between the point of contact of the two slides. Then the spreader slide is pushed forward against the first slide; the blood will form an even, thin smear. The slide is dried by waving it in the air; it should not be heated. The blood smear is covered with Wright's stain and allowed to stand 2 min. An equal amount of distilled water or buffer solution is added and mixed uniformly. It is allowed to stand 5 min. The stain is gently washed off and the slide is allowed to dry.

See: illustrationillustration

buccal smear

A sample of cells taken from the mucosa lining the cheek for chromosomal or other studies.

Pap smear

Papanicolaou test.

peripheral blood smear

Synonym: blood smear

smear

A thin film of tissue, cells, blood or other material spread on a transparent slide for microscopic examination.

Smear

A specimen prepared for microscopic study by spreading the material across a slide and treating it with a specific stain.
Mentioned in: Leprosy

smear

(smēr)
Thin specimen for examination; usually prepared by spreading material uniformly onto a glass slide, fixing it, and staining it before examination.

smear

a specimen for microscopic study, the material being spread thinly and unevenly across the slide with a swab or loop, or with the edge of another slide, e.g. blood smear, for differential white cell count, or trypanosome sighting, fecal for the presence of worm eggs or coccidial oocysts.

impression smear
one made by pressing the slide against tissue, usually the surface of a neoplasm or the cut surface of a tissue specimen.
References in periodicals archive ?
Automated slide makers/stainers with closed tube sample processing provide hands-free, walk-away smear preparation and staining.
Among 190 cases of sputum smear negative clinically diagnosed PTB cases, 33 were PTB with HIV co-infection, 11 were other previously treated cases and rest 146 were immunocompetent new sputum smear-negative PTB.
Tzanck smear is an easily performed, sensitive, specific, cost-effective and rapid test that is useful in clinical settings in dermatologist's daily practice.
Keywords: C-reactive protein, Pulmonary tuberculosis, Smear negative tuberculosis, Smear positive tuberculosis.
The current study was planned to find the ratio of false negativity in sputum samples in diagnostic smears received for acid fast bacilli (AFB) smear microscopy using culture as a standard.
The internal quality control of skin and nasal smear techniques based on a collection of specimens (staining, reading and reporting) were given top priority in the training period.
Chicago, IL, USA), with patient as the unit of analysis; [chi square]-test was used to find the statistical difference in smear positive cases between the approaches and staining techniques.
7% of patients showed smear conversion until the end of the second month and this figure reached 91.
The third is a positive smear test, which doesn't necessarily indicate cancer but means there are detectable changes in the cells which require further investigation.
Results: A total of 88 sputa were negative for acid fast bacilli on smear which were subjected to culture on Lowenstein-Jensen medium.
Don't forget, if you see your doctor with any worrying symptoms they can do a smear or, if they have a concern after examining your cervix, they can refer you to a gynaecologist at a colposcopy clinic.