smallpox vaccine


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small·pox vac·cine

vaccine of live vaccinia virus suspensions prepared from cutaneous vaccinial lesions of calves (calf lymph) or chick embryo origin; not currently used because of the worldwide elimination of smallpox.

smallpox vaccine

a vaccine prepared from dried smallpox virus. It is currently indicated only for laboratory workers and certain military personnel who could be exposed to pox viruses, but this recommendation could change with bioterrorism concerns.

small·pox vac·cine

(smawlpoks vak-sēn)
Vaccine of live vaccinia virus suspensions prepared from cutaneous vaccinial lesions of calves (calf lymph) or chick embryo origin; not currently used because of the worldwide elimination of smallpox.

smallpox vaccine

A vaccine used to provide immunity against smallpox. The vaccine is made from live vaccinia virus (not from the smallpox virus). Similarities between the two viruses make the vaccine about 95% effective in preventing smallpox in those exposed to the virus. Smallpox vaccine was not used for many years because smallpox had been eradicated worldwide. However, concerns over the use of smallpox as a biological weapon have resulted in vaccination of persons at high risk, e.g., public health workers, health care response teams, members of the armed services. The general public is not being vaccinated. The CDC recommends that persons who could be exposed to the monkeypox virus should also be vaccinated against smallpox.
See also: vaccine
References in periodicals archive ?
IMVAMUNE (MVA-BN) is a non-replicating smallpox vaccine derived from the modified vaccinia virus Ankara.
Moreover, IMVAMUNE(R) was shown to induce a comparable efficacy as ACAM2000(TM), the licensed second-generation smallpox vaccine in the US, in non-human primates.
The Centers for Disease Control (CDC) is considering a program that would give mandatory smallpox vaccines to everyone if they believe we're going to experience bioterrorist attacks.
These clinical studies have demonstrated that IMVAMUNE(R) induces a fast and strong immune response, which is comparable to that induced by traditional smallpox vaccines.
A strong vaccinia-specific immunity confirmed the potential of Imvamune[R] as a safe and effective smallpox vaccine in this population.
Bavarian has supplied several governments with smallpox vaccines and with its increased production capacity, able to supply the growing demand, particularly for safe smallpox vaccines.
Adventitious agents in smallpox vaccine in strategic national stockpile.
develop a second-generation smallpox vaccine, ACAM2000.
That finding was based on three sets of data from the National Smallpox Vaccine in Pregnancy Registry for the period between December 2002 and late April 2003 (MMWR 52[17]:386-88, 2003).
Dr Drayson acknowledged that the Lister strain vaccine supplied by PowderJect was no safer than the New York version of the smallpox vaccine developed by Acambis.
He said there were reports from decades ago in Europe of similar problems with another strain of smallpox vaccine.
He said the contracts would be big enough to protect key healthcare workers, and was optimistic larger orders would follow once the firm had won full regulatory approval for its smallpox vaccine, expected in 2004.