small vessel disease


Also found in: Acronyms.
Any of multiple small cerebral infarcts in the corona radiata, internal capsule, striatum, thalamus, basis pontis, and/or cerebellum, occasionally preceded by transient symptoms, due to occlusion or stenosis of small penetrating branches of the middle and posterior cerebral and median branches of the basilar arteries; resolution of infarcts is characterised by residual 1–3-mm cavities or lacunae, characteristic of long-standing hypertension
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

small vessel disease

Neurology Cerebrovascular disease due to stenoses in small arteries of the brain. See Ministroke.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Multiple subcortical acute ischemic lesions reflect small vessel disease rather than cardiogenic embolism.
However, only very few patients have a clear gene mutation and the cause of the majority of familial cerebral small vessel disease cases is still unknown.
Cerebral small vessel disease: Targeting oxidative stress as a novel therapeutic strategy?
To increase the chance that the lacunar stroke results from the small vessel disease, patients with evidence of a cardiac embolic source (atrial fibrillation, myocardial infarction < 6 weeks, prosthetic cardiac valve, endocarditis, cardiomyopathy, mitral stenosis, left ventricular aneurysm, or thrombus) or cerebral large vessel disease (at least 1 internal carotid artery stenosis of 50% on MR angiography or CT angiography) were excluded.
Prevalence of small vessel disease, cardioembolism, other determined etiology and undetermined etiology were found in 27,7%; 2,1%; 0,9%; and 9,8% patients, respectively.
de Laat et al., "White matter integrity in small vessel disease is related to cognition," NeuroImage: Clinical, vol.
Anterior temporal pole involvement is rare in sporadic small vessel disease. The presence of callosal commissure lesions is differentiating CADASIL from smallvessel disease [25].
Whether inflammatory processes, excluded from their involvement in large-vessel disease, are implicated in the pathogenesis of cerebral small vessel disease remains unclear.
The report provides in-depth insight into the use of DEB for coronary and peripheral applications in the lower extremity including in-stent restenosis, bifurcation lesions, small vessel disease, femoropopliteal artery and below-the-knee lesions, chronic total occlusions, acute myocardial infarction and lesions in diabetics.
* Small vessel disease, which involves the thickening and inflammation of brain blood vessels, triggers changes in brain tissue associated with cognitive impairment.
"The public health implications are significant because we are not identifying the 30% who have undiagnosed small vessel disease that is not picked up by current technology.
"There is a very big public health consequence because we're not capturing this 30 percent who have undiagnosed small vessel disease that is not picked up by current technology.

Full browser ?