small round cell tumour

small round cell tumour (adult)

A generic term for a malignancy composed of small (< 14 µm in diameter) round cells.

Examples
Neuroblastoma, rhabdomyosarcoma, lymphoma, mesenchymal chondrosarcoma, poorly differentiated synovial sarcoma, Ewing sarcoma, small cell carcinoma of lung, Merkel cell carcinoma, melanoma. The term is by definition non-specific: ancillary studies, especially immunohistochemistry, are mandatory to identify specific tumour antigens.

Small round cell tumour panel
S-100, CK, LCA.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
Rollan, "Intraabdominal desmoplastic small round cell tumour," Pediatric Surgery International, vol.
A variety of tumours have overlapping morphological features such as EWS, rhabdomyosarcoma, lymphoma, desmoplastic small round cell tumour, etc.
Ewing's Sarcoma (ES) is a small round cell tumour and accounts for one quarter of all primary bone tumours during childhood.
Brigstock, "Expression of connective tissue growth factor (CCN2) in desmoplastic small round cell tumour," Journal of Clinical Pathology, vol.
Sotti et al., "Desmoplastic small round cell tumour in children and adolescents," Medical and Pediatric Oncology, vol.
In some cases, like suspected small round cell tumour (Ewing's sarcoma), special stains like periodic acid schiff staining was also performed on tissue sections for confirmation.
Peripheral primitive neuroectodermal tumour (PNET) is a rare malignant small round cell tumour of neuroectodermal origin with variable cellular differentiation (1,2).
Specificity of the EWS/WT1 gene fusion for desmoplastic small round cell tumour. J Pathol.
A morphologic diagnosis of small round cell tumour, possibly olfactory neuroblastoma in the right nasal cavity was made, bearing in mind the age of the patient, location of the tumour and the presence of rosette-like structures on microscopy.
Moskovic, "Desmoplastic small round cell tumour: the radiological, pathological and clinical features," Insights into Imaging, vol.
A picture of small round cell tumour with PAS positivity and CD 99 was helpful in finalizing the diagnosis.
The microscopic diagnosis was malignant, small round cell tumour, hemithorax.

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