small nuclear RNA

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Related to small nuclear RNA: Micro RNA

small nu·cle·ar RNA (snRNA),

small RNA (that is, about 90-300 nucleotides long) in the nucleus believed to have a role in RNA processing and cellular architecture.

small nuclear RNA (snRNA)

short eucaryotic RNA molecule found in the nucleus, involved in the SPLICING of specific types of INTRON in PRIMARY mRNA molecules. Also called U-RNA, since it is rich in URIDINE NUCLEOTIDES.

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During my phD, I identified RNA ligands for the magnesium ions that catalyze these splicing reactions and showed that the spliceosomal U6 and U2 small nuclear RNAs form a structure resembling group II self-splicing intron RNAs.

SpliceosomeStructure: Structural role of protein splicing factors in promoting an active configuration of the spliceosome~s RNA catalytic core