small interfering ribonucleic acid

small interfering ribonucleic acid

a class of small RNA that inhibits RNA transcription.
See also: small ribonucleic acid, ribonucleic acid interference.
References in periodicals archive ?
Various pharmaceutical means are being developed to inhibit PCSK9.6 These include small monobodies, oral peptides, antisense oligonucleotides, and small interfering ribonucleic acid (SIRNA).
APN401 is an individual adoptive cell therapy in which human peripheral blood mononuclear cells are silenced ex- vivo for Cbl-b (an E3 ubiquitin ligase) using small interfering ribonucleic acid (siRNA), thereby activating them to fight cancer more efficiently.
Various methods to inhibit apoptosis including the cell surface Fas receptor (FAS) pathway inhibitors (also known as CD95L pathway inhibitor), caspase inhibitors, overexpression of anti-apoptotic genes and small interfering ribonucleic acid (RNA) therapy are discussed.

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