small blue round cell tumour

small blue round cell tumour

A generic term for tumours (almost invariably malignant) characterised by sheets of relatively homogenous small cells with scant cytoplasm and prominent (“blue”) nuclei, which cannot be reliably differentiated by light microscopy and require ancillary studies—in particular, immunohistochemistry—to identify cell lineage and guide therapy.

Head and neck SBRCTs
Lymphoma, melanoma, olfactory neuroblastoma, peripheral neuroendocrine tumour, rhabdomysarcoma, sinonasal undifferentiated carcinoma.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
"We are not ready to give up on him yet." The cancer - a rare type of undifferentiated small blue round cell tumour, with germ cell solid tissue tumours - was found lining Connor's stomach three years ago.
On her return, scans revealed a desmosplastic small blue round cell tumour - an aggressive and rare soft cell sarcoma that has a five-year survival rate of just 15%.
Identification of these tumours is important to help guide the treatment strategy, as rapid therapy is required and the diagnosis of small blue round cell tumours is broad.