Ancelin et al., "Insomnia, daytime sleepiness
and cardio-cerebrovascular diseases in the elderly: a 6-year prospective study," PLoS One, vol.
Repeated measures of finger dexterity and sleepiness
were done at fixed intervals of 0, 6, 12, 18, and 24 h of SD.
The use of the scale had been practice beforehand and consisted of the following scores: 1 = extremely alert, 2 = very alert, 3 = alert, 4 = rather alert, 5 = neither alert or sleepy, 6 = some sign of sleepiness
, 7 = sleepy, but no effort to stay awake, 8 = sleepy, some effort to stay awake, 9 = very sleepy, great effort to stay awake.
Therefore, the purpose of this study was to assess the prevalence of excessive daytime sleepiness
(EDS) measured by the Epworth Sleepiness
Scale (ESS) among academic physicians at a tertiary academic medical center in an urban area in the northwest region of Turkey, and to establish the relationship between the self-perceived sleepiness
and the quality of life using the EuroQol-5 dimensions (EQ-5D).
Poor sleep quality was associated with female gender (p less than 0.05), excessive daytime sleepiness
(p less than 0.05), total hours slept (p less than 0.001) and sleep disturbances (p less than 0.001).
A score greater than 10 on the Epworth Sleepiness
Scale (ESS), or a mean sleep latency less than eight minutes on the Multiple Sleep Latency Test (MSLT) (30,41,42) is considered inappropriate sleepiness
during waking hours and has been under-recognized in PD.
Moreover, the only E2006 group to show a statistically significant increase compared to placebo in next-day residual sleepiness
as measured by the Karolinska Sleepiness
Scale (KSS) was at the dose of 25 mg.
For the study, more than 600 nurses working full-time in critical care units completed a questionnaire on personal and work-related data, sleep quality, daytime sleepiness
, sleep quantity, clinical-decision self-efficacy, and decision regret.
Sleep apnea tends to produce excessive daytime sleepiness
but this study recruited patients with insomnia, and most with insomnia don't have sleep apnea, rather issues like anxiety, stress and depression and so other emotional and psychological factors are more likely interfering with their sleep.
Health care utilization was not significantly predicted by sleepiness
. Higher disability, pain intensity, and presence of a sleep disorder were associated with higher predicted visits and costs for LBP.
To probe for the culprit of daytime sleepiness
, actigraphy wrist monitoring was performed and showed no persistent insomnia or circadian rhythm disturbances.
Approval was based on results from TONES (Treatment of Obstructive Sleep Apnea and Narcolepsy Excessive Sleepiness
), a phase 3 study that combined four randomized, placebo-controlled trials assessing solriamfetol at various doses, compared with a placebo.