The severity of the sleep apnoea itself, the experience of daytime sleepiness, the alteration in sleep stages and sleep architecture, obesity, sleep fragmentation
and hypoxaemia (32) may alone or in combination cause the reduction in quality of life that has been observed in sleep apnoea patients.
The difference between the two groups could reflect individual differences in the way sleep fragmentation affects daytime function, or it might be that many individuals simply do not recognize their degree of sleepiness and therefore do not report it.
By the early 1990s, Guilleminault et al described patients who experienced sleep fragmentation and daytime sleepiness, but who did not experience the obvious apneic or hypopneic events that caused the brief arousals that were observed.
Correction of these characteristics will prevent airflow limitation and decrease the ventilatory effort, obstruction, arousal, and sleep fragmentation
that occur with OSA.
Twenty five percent of middle-aged men are affected by sleep apnoea, and almost three per cent of them experience a severe form of the condition characterised by extended pauses in breathing, repetitive asphyxia and sleep fragmentation
In contrast, a patient afflicted with more severe symptoms, including cataplexy, hypnagogic hallucinations and sleep fragmentation may require a more aggressive pharmaceutical paradigm.
In summary, narcolepsy is a complex disorder with multiple symptoms including excessive daytime sleepiness, cataplexy, hypnagogic hallucinations, sleep paralysis and sleep fragmentation.
increase sleep fragmentation
and absenteeism from work and decrease
Their hypersomnolence was primarily the result of sleep fragmentation
caused by SDB.
Although it is unlikely that OSA causes dementia, the lowered oxygen levels and sleep fragmentation
associated with OSA might worsen cognitive function," said Lead researcher Sonia Ancoli-Israel, Ph.
The physiologic variables that are evaluated in a standard polysomnogram include changes in oxygen saturation, cardiac arrhythmias, arousals caused by respiratory events, and sleep fragmentation
caused by frequent arousals.
Nicotine increases sleep latency and sleep fragmentation