skip lesion

skip lesion

Any lesion in which normal tissue is interspersed with tissue affected by a pathologic condition. Skip lesions occur in metastatic carcinoma, polyarteritis nodosa (interspersed “skipping” or sparing of vessels), Crohn’s disease (interspersing of involved and relatively normal intestine), radiologically and on gross examination; it is regarded as a “classic” feature, but only occurs in 20–25% of cases.
References in periodicals archive ?
One night, after finding out that a skip lesion had been left behind during the first cancer surgery, my older sister came to me with furrowed brows, visibly concerned.
* To establish whether the lesion is benign or malignant, presence of a lesion or skip lesion in surgically suspicious tissue area.
The existence and localization of the skip lesion was first confirmed by transthoracic and transesophageal echocardiography.
No skip lesion was noted at the time of laparotomy.
This finding lends support to the appendicial "skip lesion" hypothesis.
Typical UC involves the rectum and extends proximally continuously without skip lesion. However, several atypical features may lead to misdiagnosis as CD.
(4) CD is one of the most common inflammatory bowel diseases and is characterized by chronic, relapsing, remitting, inflammation that may have skip lesions mainly in the small and large intestine.
On the other hand, the concern of possible malignant potential in CMPTs comes from focally destroyed alveolar structures, central fibrosis, proliferation along the alveolar walls, the existence of skip lesions, the lack of encapsulation, the presence of a micropapillary pattern, and positive immunostaining for CEA.
Osteosarcomas may have skip lesions, which are osseous or marrow metastasis within the same bone or adjacent bones in relation to the dominant lesion.
It is associated with increased local recurrence, possibly due to perineural skip lesions or missed areas of positive margin [24, 25].
Simultaneous sites of disease may also represent more concerning pathology such as osteosarcoma with skip lesions or other metastatic bone disease.