skip lesion

Any lesion in which normal tissue is interspersed with tissue affected by a pathologic condition. Skip lesions occur in metastatic carcinoma, polyarteritis nodosa (interspersed “skipping” or sparing of vessels), Crohn’s disease (interspersing of involved and relatively normal intestine), radiologically and on gross examination; it is regarded as a “classic” feature, but only occurs in 20–25% of cases.

References in periodicals archive ?

One night, after finding out that a skip lesion had been left behind during the first cancer surgery, my older sister came to me with furrowed brows, visibly concerned.

Knowing

The tubal lesion is a skip lesion. Cervical leiomyosarcoma is indicated by arrows.

Coexistence of Cervical Leiomyosarcoma and Gastric-Type Adenocarcinoma In Situ with Extensive Extension to the Endometrium and Fallopian Tube

* To establish whether the lesion is benign or malignant, presence of a lesion or skip lesion in surgically suspicious tissue area.

REVIEW OF INTRA-OPERATIVE FROZEN SECTION AND ITS ROLE IN SURGICAL EXCISION OF BASAL CELL CARCINOMA (BCC)

The existence and localization of the skip lesion was first confirmed by transthoracic and transesophageal echocardiography.

A case of pulmonary sarcoma with significant extension into the right lung

No skip lesion was noted at the time of laparotomy.

Unusual presentation of Crohn's Disease

This finding lends support to the appendicial "skip lesion" hypothesis.

Appendectomy effective for refractory ulcerative colitis. (Small Study)

Typical UC involves the rectum and extends proximally continuously without skip lesion. However, several atypical features may lead to misdiagnosis as CD.

Clinical Aspects of Idiopathic Inflammatory Bowel Disease: A Review for Pathologists

(4) CD is one of the most common inflammatory bowel diseases and is characterized by chronic, relapsing, remitting, inflammation that may have skip lesions mainly in the small and large intestine.

Takeda Pharmaceutical Company Limited - Entyvio[R] (vedolizumab) Approved in Japan for the Treatment of Patients with Moderately to Severely Active Crohn's Disease -- 22/5/2019

On the other hand, the concern of possible malignant potential in CMPTs comes from focally destroyed alveolar structures, central fibrosis, proliferation along the alveolar walls, the existence of skip lesions, the lack of encapsulation, the presence of a micropapillary pattern, and positive immunostaining for CEA.

Ciliated Muconodular Papillary Tumors of the Lung

Osteosarcomas may have skip lesions, which are osseous or marrow metastasis within the same bone or adjacent bones in relation to the dominant lesion.

Pediatric bone imaging: Differentiating benign lesions from malignant

It is associated with increased local recurrence, possibly due to perineural skip lesions or missed areas of positive margin [24, 25].

Essential Components of Melanoma Histopathological Reporting: The Surgical Oncologist's Perspective

Simultaneous sites of disease may also represent more concerning pathology such as osteosarcoma with skip lesions or other metastatic bone disease.