biotin

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biotin

 [bi´o-tin]
a sulfur-containing member of the vitamin B complex that plays an essential role in gluconeogenesis and the synthesis of fatty acids. Food sources include liver, egg yolk, soy flour, cereals, and yeast. For recommended daily intake, see Section 4 of the appendices. See also vitamin.

bi·o·tin

(bī'ō-tin),
The d-isomer component of the vitamin B2 complex occurring in or required by most organisms and inactivated by avidin; participates in biologic carboxylations. It is a small molecule with a high affinity for avidin that can be readily coupled to a previously labeled antibody to allow visualization by enzymatic or histochemical means.
See also: avidin.

biotin

(bī′ə-tĭn)
n.
A vitamin, C10H16N2O3S, that is a component of the vitamin B complex and is a cofactor in many enzyme systems. It is found in large quantities in liver, egg yolk, milk, and yeast and is used in many biotechnology applications.

biotin

A water-soluble B vitamin.

Biochemistry
Biotin is the d-isomer of vitamin-B2 complex, which is a prosthetic group for carboxylase enzymes and important in fatty acid biosynthesis and catabolism. It is present in and essential for most animals, as it participates in carboxylation; daily requirements are in the mg range; biotin deficiency is rare.
 
Lab medicine
Biotin is widely used as a covalent label for macromolecules which are detected by high-affinity binding of labelled avidin or streptavidin.

Molecular biology
Biotin can be incorporated into dUTP and used as a non-radioactive label for a DNA probe. It is used to label nucleic acids and proteins that may be subsequently detected by avidin or streptavidin linked to a fluorescent or enzymatic reporter molecule.

bi·o·tin

(bī'ō-tin)
The d-isomer component of the vitamin B2 complex occurring in or required by most organisms and inactivated by avidin; participates in biologic carboxylations.

biotin

A water-soluble B vitamin concerned in the metabolism of fats and carbohydrates. Deficiency causes DERMATITIS, muscle pain, loss of appetite and ANAEMIA.

biotin

a water-soluble vitamin of the B-COMPLEX present in many foods, including yeast, liver and fresh vegetables. Biotin acts as a COENZYME in amino acid and lipid METABOLISM. A deficiency (rare in humans) of biotin causes dermatitis and intestinal problems.

bi·o·tin

(bī'ō-tin)
The d-isomer component of the vitamin B2 complex occurring in or required by most organisms and inactivated by avidin.
See also: avidin
References in periodicals archive ?
Caption: FIGURE 15: The effect of skin factor on type curves.
The skin factor of individual layer and layer 1 permeability acquired by interpreting field test data are consistent with the actual situation of oilfield, which further prove that our model can accurately interpret Field Test Two and evaluate formation.
Injection rate q ([m.sup.3]/d) 100 Layer 1 thickness [h.sub.1] (m) 8 Layer 2 thickness [h.sub.2] (m) 6 Oil volume factor [B.sub.0] 1.1037 Porosity [phi] 0.3 Crude oil viscosity [[micro].sub.o] 14.2 (mPa x s) Brine viscosity [[micro].sub.w] 0.5 (mPa x s) Temperature [degrees]C 75 Total compressibility [C.sub.t] (1/MPa) 0.0014 Well radius [r.sub.w] (m) 0.1 Layer 1 permeability before polymer mD 1592 flooding Layer 2 permeability before polymer mD 1466 flooding Layer 1 skin factor before polymer n/a 1.11 flooding Layer 2 skin factor before polymer n/a 1.18 flooding TABLE 6: Interpretation results of Field Test One (Well 5-227).
The purpose of this study is to establish well testing interpretation method that can be applied in crossflow double-layer reservoir by polymer flooding, by considering shear, diffusion, convection, IPV, permeability reduction, wellbore storage effect, and skin factors. Moreover, field test data are further interpreted by this method for formation evaluation and EOR.
Based on the rheological model and hypotheses discussed above, the well testing interpretation model in crossflow double-layer reservoir by polymer flooding is established, by considering shear, diffusion, convection, IPV, permeability reduction, wellbore storage effect, and different layered skin factors:
The effect of crucial parameters (e.g., production rate distribution, the length of HW, the length of PS, the number of PS, PS spacing, skin factor, and anisotropy degree) is shown in Figures 5-12.
Parameters (e.g., length, production rate, and skin factor of each PS) distribute uniformly along HW, and the total production rate remains constant for different cases.
The total skin factor and total production rates are kept constant for different cases.
In the following cases, other parameters (e.g., total production rate, the number of PS, and skin factor of each PS) are constant.
Skin Factor. A horizontal well with the length of 1000 m consists of four segments with the same length of PS ([L.sub.wiD] = 0.1) and PS spacing ([DELTA][x.sub.D]).
Variable Total Skin Factor of PS (Equal Skin Factor of Each PS).