Glycation associated skin autofluorescence
and skin elasticity are related to chronological age and body mass index of healthy subjects.
Simultaneously, during last followup, we measured the advanced glycation end products (AGE) in the skin autofluorescence
(SAF), using AGE Reader by Diagnoptics in order to assess the risk of diabetes mellitus development as a possible cause of the dyschromatopsia in fellow eyes without fundoscopic changes and with good visual acuity.
AGE accumulation can be assessed by skin autofluorescence
(SAF) following the principles of AGE Reader, which is a validated and noninvasive technique.
, a measurement of cutaneous advanced glycation end products, can be used as a screening method in detecting unknown diabetes.
(SAF) measure is a promising noninvasive method to evaluate AGE deposition which correlated with AGE levels determined by biochemical analysis of skin biopsies .
, relatively simple and time saving procedure, is related to the accumulation of AGE products and is one of the strongest markers to predict cardiovascular events in diabetes, renal insufficiency, and atherosclerosis itself .
The comparison of skin autofluorescence
intensity image and image of autofluorescence photobleaching rates, both extracted from the skin video at UV-illumination, is illustrated at Fig.
West recently presented preliminary data from a human clinical trial on skin autofluorescence
, a non-invasive AGE marker.
Reconstruction of in vivo skin autofluorescence
spectrum from microscopic properties by Monte Carlo simulation.
Palcic, "Recon struction of in vivo skin autofluorescence
spectrum from microscopic properties by Monte Carlo simulation," Journal of Photochemistry and Photobiology B, vol.
COPENHAGEN -- Skin autofluorescence
is a strong and independent predictor of mortality in patients with well-controlled type 2 diabetes, according to data presented at the annual meeting of the European Association for the Study of Diabetes.
Using the same properties, a noninvasive method has been developed for assessing accumulation of AGEs in dermal proteins by measuring skin autofluorescence
with a dedicated device.