size fractionation


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size fractionation

The separation of substances in a mixture on the basis of their molecular size, e.g., the separation of DNA strands based on their number of nucleotides.
See also: fractionation
References in periodicals archive ?
Genotyping fetal paternally inherited SNPs by MALDI-TOF MS using cell-free fetal DNA in maternal plasma: influence of size fractionation.
Agilent's novel method for efficiently labeling miRNA in total RNA eliminates tedious size fractionation and requires only 100 nanograms of input RNA from precious samples.
Furthermore, the reported method for such size fractionation is based on the size separation of plasma DNA using agarose gel electrophoresis, followed by the extraction of DNA from manually cut agarose gel slices containing different size fractions (7).