sitostanol

sitostanol

(sī-tō-stān'ol),
A plant sterol used as a cholesterol-lowering agent.
References in periodicals archive ?
Phytosterol, [alpha]-sitosterol, and sitostanol have also been shown to suppress Th2 cytokine production and AHR in mice [28].
TC: total carbon; TN: total nitrogen; TP: total phosphorus; OM: organic matter; C[O.sub.3]=: carbonates; CO: coprostanol; EP: epicoprostanol; CH: cholesterol; CHL: cholestanol; CA: campesterol; CAL: campestanol; ST: stigmasterol; STL: stigmastanol; DI: dinosterol; SI: sitosterol; SIL: sitostanol. Nortes season (Feb'12) n = 12 Median Min Max Sediment nutrients (%) TC 13.27 12.02 19.66 TN 0.75 0.36 1.53 TP 0.06 0.04 0.07 OM 12.65 6.08 36.87 C[O.sub.3.sup.=] 36.17 18.41 40.97 Sterols [micro]g [g.sup.-1] D.
Thirteen sterols (cholesterol, brassicasterol, 24-methylene-cholesterol, campesterol, campestanol, stigmasterol, [[DELTA].sup.7]-campesterol, [[DELTA].sup.5,23]-stigmastadienol, clerosterol, [beta]-sitosterol, sitostanol, [[DELTA].sup.5]-avenasterol, and [[DELTA].sup.5,24]-stigmastadienol) were identified in oil based on their relative retention times with respect to the internal standard, cholestanol, according to the standardized reference method (EEC, 1991, Annexes V and VI).
One study examined the effects of plant stanols on fasting apoA-I concentrations and found increased apoA-I concentrations comparing 6 weeks of sitostanol consumption with no sitostanol consumption [105].
There are approximately 200 phytosterols, among which [beta]-sitosterol, campesterol, and sitostanol are the major ones [30].
A commercial phytosterol preparation containing [sz]-sitosterol, campesterol, sitostanol and campestanol was added at a 1.8% concentration to pasteurized milk.
Technical [beta]-sitosterol (~60%, SigmaAldrich) was chosen as a reference mixture as it contains two other phytosterols (campesterol and sitostanol) which can be used for further authentication of chromatographic peaks in natural samples.
Plant sterols such as sitostanol can reduce the body's absorption of cholesterol, thereby reducing serum blood levels and aiding in the decrease in the risk of cardiovascular disease.
A commercial phytosterol preparation (CPP) containing [beta]-sitosterol, campesterol, sitostanol and campestanol was added at a concentration of 1.8% (w/v) to pasteurized milk.