site-specific recombination


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site-spe·cif·ic re·com·bi·na·tion

integration of foreign DNA into a particular site in the host genome.

site-spe·cif·ic re·com·bi·na·tion

(sīt-spĕ-sif'ik rē-kom'bi-nā'shŭn)
Integration of foreign DNA into a particular site in the host genome.
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References in periodicals archive ?
In both prokaryotic and eukaryotic organisms, various site-specific recombination reactions are conserved, and these systems generally involve specific enzymes and unique asymmetric DNA sequences [8-10].
These pleiotrophic effects include deregulation of type 1 site-specific recombination.
Genetically, the differences occurred in tcpA, which encodes the major adherence antigen rstR that regulates site-specific recombination of CTX9 phage and ctxB that encodes the B subunit of cholera toxin.
Gateway(r) Technology, developed by Invitrogen, is a universal cloning method which uses the site-specific recombination properties of bacteriophage lambda (Landy, 1989).
Taking the dream one step closer to industrial reality, the team has developed data proof-read/correction and random access modules, in addition to an encryption module, all using site-specific recombination of the inversion type, specifically, R64 Shufflon-Specific Recombinase, a type of Rci-mediated recombination.
Johnston, IA) has patented methods of controlling gene silencing using site-specific recombination.
One of the most efficient procedures for generating single-copy plants is site-specific integration of foreign genes mediated by heterologous site-specific recombination systems (Albert et al.
Remaining chapters discuss the use of homologous recombination and site-specific recombination to disrupt or modify endogenous genes and genomes; strategies for controlling transgene expression; position effects, dosage effects, genetic background, transgene structure, and other aspects of transgene behavior that can generate unexpected results in gene transfer experiments; the use of gene transfer to achieve the targeted or random inactivation of endogenous genes; and the major application of gene transfer, including commercial synthesis of recombinant proteins, domestic animal improvement, disease modeling, and gene therapy.
DNA-dependent protein kinase activity is absent in xrs-6 cells: Implications for site-specific recombination and DNA double-strand break repair.
High-efficiency FLP and [PHI]C31 site-specific recombination in mammalian cells.
Integrons are efficient gene-capture systems by site-specific recombination and are involved in antimicrobial-drug resistance in gram-negative bacteria (2).