Site-specific mutation | definition of site-specific mutation by Medical dictionary
an alteration of the structure of a gene at a specific sequence, usually referring to experimentally produced changes in gene sequence.
References in periodicals archive
of the interferon sensitivity-determining region (ISDR) modulates hepatitis C virus replication.
I will then test the biological impact of ADPR of these candidates through site-specific mutation
of their identified modification sites.
The fourth variant incorporates all of the above changes and two additional site-specific mutations
, T22C and S87C that form a stabilizing disulfide bridge.