site-specific mutation

site-spe·cif·ic mu·ta·tion

an alteration of the structure of a gene at a specific sequence, usually referring to experimentally produced changes in gene sequence.
References in periodicals archive ?
Myriad will transfer technical know-how for site-specific mutation detection to Bioscientia.
Site-specific mutations of the enzyme were used to further augment the signal generated by fragment complementation.
The fourth variant incorporates all of the above changes and two additional site-specific mutations, T22C and S87C that form a stabilizing disulfide bridge.
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