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Despite conserved deacetylase domains, mitochondrial sirtuin 4 (Sirt4) is the most efficient lipoamidase among mitochondrial sirtuins.
ALT: Alanine aminotransferase AST: Aspartate aminotransferase BMI: Body mass index DBP: Diastolic blood pressure HDL: High-density lipoprotein HoMA-IR: Homeostatic model assessment-insulin resistance HS: Hepatic steatosis INQ: Index of nutritional quality LDL: Low-density lipoprotein MAI: Mediterranean adequacy index MD: Mediterranean diet MUFA: Monounsaturated fatty acids PREDIMED: PREvencion con DIeta MEDiterranea PUFA: Polyunsaturated fatty acids RI: Recommended intake ROS: Reactive oxygen species SBP: Systolic blood pressure SFA: Saturated fatty acids Sirt4: Sirtuin 4 TG: Triglycerides VAI: Visceral adiposity index WC: Waist circumference [gamma]GT: Gamma glutamyl transferase.
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Sirt4: sirtuin 4; PREDIMED: PREvencion con DIeta MEDiterranea.