CF is characterized by the classic triad of elevated sweat chloride levels, chronic sinopulmonary
disease, and pancreatic insufficiency.
The other patient with TNFRSF13B C104R mutation had frequent sinopulmonary
infections since he was 12 years of age.
CVID usually presents in childhood with recurrent sinopulmonary
infections, and respiratory morbidity is common, ranging from recurrent suppurative bronchitis to bronchiectasis [3, 4].
A 5-year-old male initially came to the attention of the immunology service at 2 years of age with a history of recurrent sinopulmonary
infections and a family history of XLP1 (nonsense mutation c.
The spectrum of mucormycosis ranges from localized rhinocerebral, sinopulmonary
, and cutaneous disease to disseminated infections .
Gupta and colleagues have hypothesized that patients with YNS have frequent sinopulmonary
infections due to immunodeficiency.
In addition, stress, weight loss, strenuous exercise, psychological stress, and systemic chronic illnesses may also be associated with FHA.[sup], Our patient suffered from recurrent sinopulmonary
infection that caused the body's endocrine disorders and exerted stress on physiologically and mentally to some extent.
Other than bacterial sinopulmonary
infections, tuberculosis was the most frequent opportunistic infection (n=3, 13.6%).
Patients with SIGAD generally have an increased risk of sinopulmonary
infections, allergy, and auto-immune conditions.
His history revealed that he had suffered from eczematous skin lesions, recurrent skin bursts, and sinopulmonary
infections since early childhood and recurrent generalized HSV infection.
Ataxia Telangiectasia (AT) is an autosomal recessive syndrome characterised by progressive cerebellar ataxia, immune-deficiency, which usually takes the form of sinopulmonary
infections, oculocutaneous telangiectasia, Xray hypersensitivity and predisposition to lymphoid malignancies.
It has been reported that severe acne is related with higher frequencies of gastrointestinal, sinopulmonary
, and psychological disorders.