Xanthohumol showed the highest activity in total oxygen radical absorbance capacity as well as singlet oxygen
Buettner, "Molecular targets of photosensitization--some biological chemistry of singlet oxygen
," in Photobiology Sciences on Line, K.
is one of the strongest reactive oxygen species (ROS) that damages biological lipids, proteins and DNA.
The resulting oxidant injury is not thought to be mediated by singlet oxygen
(Chiarpotto et al.
The production of singlet oxygen
is an important key in the successful application of both OPE- and TPE-PDT.
is known to oxidize bacterial proteins or lipids, thereby causing the death of affected bacteria.
Their role is probably to filter out phototoxic blue light and to quench singlet oxygen
In 2003, Brunswick Laboratories received a Small Business Innovation Research (SBIR) grant from the USDA to develop ORAC assays for singlet oxygen
, hydroperoxide and superoxide anion.
Reduced glutathione, which is a substrate for glutathione peroxidase, neutralizes hydroxyl radicals and singlet oxygen
It is known that oxygen reactive species (subperoxide, perhydroxide, hydrogen peroxide, hydoxyl, singlet oxygen
, peroxyl) and also nitrogen reactive species play key roles in skin disorders, including cancer, psoriasis and photoaging.
Although [beta]-carotene is an excellent quencher of singlet oxygen
photogenerated in plants and certain bacteria, we were intrigued how [beta]-carotene might function as an antioxidant in mammalian cells.