single-fibre electromyography

single-fibre electromyography

A procedure used to evaluate the activity of single fibres of selected muscles (e.g., common extensor of fingers) displayed as an action potential on a cathode-ray oscilloscope.

Indications
Detection of early defects in neuromuscular junction diseases (e.g., myasthenia gravis, Eaton-Lambert syndrome, botulism) when a clinical (neurologic) exam is still normal.

Method
SF-EMG consists of insertion of small (25 µm in diameter) wire into a superficial muscle, and evaluation of muscle jitter and fibre density.
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References in periodicals archive ?
Brain magnetic resonance imaging, chest X-rays, neck computed tomography, and single-fibre electromyography showed no distinct pathology.