Notably, most authors who took up the double-blind option saw it as fairer than single-blind
CAPTION: Note: Based on 12-month follow-up data from a randomized, single-blind
clinical trial that included 93 patients with mild to moderate knee osteoarthritis.
Cohort II is a randomized, controlled, single-blinded
cohort in forty AIS-B subjects.
Data source: The PRIDE study was a prospective, multicenter, open-label single-blind
study in which 450 schizophrenia patients with contact with the criminal justice system within the last 90 days were randomized to long-acting injectable paliperidone palmitate or daily oral antipsychotic therapy.
Data source: A secondary analysis of a single-blind
randomized trial of 150 women undergoing vaginal prolapse surgery.
The form of peer review that a journal uses--open, single-blind
, or double-blind--and the details of the review process are vital aspects of proper peer-review ethics and etiquette, in addition to overall journal quality.
The study was limited by a small sample size, the single-blind
design, and the fact that it was done over two flu seasons during which two of the three strains tested changed from year 1 to year 2.
In a single-blind
, randomized trial, 66 patients with fibromyalgia participated twice a week over the course of 12 weeks in one-hour Tai Chi lessons or in one-hour educational sessions in order to see whether the classes had any benefit in relieving pain.
To study the effectiveness of hypnosis for decreasing antiemetic medication usage and treatment of chemotherapy-related nausea and vomiting in children with cancer, we conducted a prospective, randomized, and controlled single-blind
trial in 20 patients receiving chemotherapy for treatment of cancer.
The researchers generally preferred double-blind review to the current standard of single-blind
review as an improvement to the objectivity and fairness of the system.
The COSTAR II clinical trial is a randomized, single-blind
, non-inferiority study comparing Conor Medsystems' CoStar(R) cobalt chromium paclitaxel-eluting stent with Boston Scientific's Taxus(R) Express2 drug- eluting stent in the treatment of de novo lesions in patients with single or multi-vessel coronary artery disease.