Harrison, "The structure of simian virus 40
refined at 3.1 A resolution," Structure, vol.
Case-control study of simian virus 40
and non-Hodgkin lymphoma in the United States.
Human cell transformation by simian virus 40
. In Vitro, 17: 1-19.
Does simian virus 40
DNA integrate into cellular DNA during productive infection?
Diethyl pyrocarbonatetreated, RNase-free water (Biotecx Labs, Houston, Tex) was used as the negative control; the positive controls were DNA extracted from brain tissue from a patient with PML (for JCV), renal tissue from a patient with histologically proven BKV nephropathy (for BKV), and from an simian virus glia cell line culture (for simian virus 40
Characterization of human uroepithelial cells immortalized in vitro by simian virus 40
. Cancer Res 47:6066-6073 (1987).
Lack of serologic evidence for prevalent simian virus 40
infection in humans.
This stain, which was also positive in the present case (not shown), is performed on paraffin-embedded tissue using an antibody against simian virus 40
, which cross-reacts with other polyomaviruses. So far, only in situ hybridization allows BK virus-specific detection using a probe that does not cross-react with other members of the polyomaviruses.
The coat on simian virus 40
contains a total of 360 proteins.
In every construct, the tag sequence included codes for the 11-aa KPPTPPPEPET epitope of simian virus 40
(SV40) large T-antigen (31,32).
Furthermore, alterations of tumor suppressor genes p16/CDKN2A-[P14.sup.ARF] at 9p21 and NF2 at 22q12 are often encountered in MMs. Simian virus 40
may act in conjunction with asbestos, since approximately 60% of analyzed MMs show expression of simian virus 40
at the molecular level.6 Additionally, the pathogenesis of asbestos-associated injury involves the participation of a number of cell types and is characterized by an early and persistent inflammatory response that involves the generation of oxidants, growth factors, chemokines, and cytokines.
Simian virus 40
in polio vaccine: follow-up of newborn recipients.