silver stain

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sil·ver stain

any of a variety of stains (for example, Bielschowsky, Gomori silver, impregnation stains) that employ alkaline silver nitrate solutions to stain connective tissue fibers (reticulin, collagen), calcium salt deposits, spirochetes, neurologic tissue, and nucleolar organizer regions.
A metallic silver-based stain which is used to highlight basement membranes, and is of greatest use in glomerulonephritides, many of which have thickening or other glomerular basement membrane changes


1. a chemical element, atomic number 47, atomic weight 107.870, symbol Ag. See Table 6. It is used in medicine for its caustic, astringent and antiseptic effects. Experimental poisoning with silver salts causes myopathy.
2. a coat color in dogs, foxes.

silver amalgam
see amalgam.
silver collie syndrome
see canine cyclic hematopoiesis.
silver grass
silver halide
any of the silver salts with halogens including bromine, chlorine, iodine used in photographic emulsion.
silver iodide
soluble silver salt used in cloud seeding but presents no toxicological risk to local grazing cattle.
silver-leaf ironbark
silver-leafed nightshade
silver nitrate
colorless or white crystals, used as a caustic and local anti-infective.
silver nitrate (toughened)
a mixture of silver nitrate with hydrochloric acid, sodium chloride or potassium nitrate, occurring as white crystalline masses molded into pencils or cones, called caustic pencils; a convenient means of applying silver nitrate locally. Called also lunar caustic.
silver protein
silver made colloidal by the presence of, or combination with, protein; an active germicide with a local irritant and astringent effect.
silver stain
a method of demonstrating flagella on bacteria, or for visualizing very thin bacteria, such as leptospires.
silver sulfadiazine
the silver salt of sulfadiazine, having bactericidal activity against many gram-positive and gram-negative organisms, as well as being effective against yeasts; used as a topical anti-infective for the prevention and treatment of wound sepsis in patients with second and third degree burns.
silver weed
References in periodicals archive ?
Silver stain shows double contours, reflecting mesangial cell interposition with the production of extraneous GBM-like material, referred to as tram-tracking, splitting, or duplication of the GBM in both types-I and -II MPGN.
The confirmation of the absence of any contamination of membrane proteins in the purified SGPs (Figure 3A and C, lane 2) was done by silver stain (Figure 3C, lane 2) which is visualizing only the purified SGPs in the gel.
8,9) Senile or neuritic plaques, which are composed of tortuous neuritic processes surrounding a central amyloid core, are best visualized using silver stains or immunohistochemistry for amyloid beta (A[beta]) protein.
Although we did not confirm CSF leakage with invasive procedures, we interpreted the two discordant samples as illustrating the lack of sensitivity of the immunofixation/ silver stain method (method 1) compared with the other methods as well as the difficulty of the nephelometric procedure for classifying borderline abnormal results.
Although the patient in our case was not known to have AIDS at the time of diagnosis, the microscopic findings of the granular, frothy, pink material and associated granulomatous feature prompted a test with Grocott methenamine silver stain.
Sections were immunostained with modified Bielschowsky silver stain and a commercially available monoclonal human amyloid-[beta] antibody for the detection of amyloid-[beta] in cerebral vessels.
Silver stain and DFA were negative, as were tests for other respiratory pathogens.
Beta amyloid was evaluated using Bielschowsky silver stain and/or the beta amyloid peptide specific antibody 4G8.
Methenamine silver stain showed numerous yeasts measuring approximately 4 to 10 [micro]m (Fig.
4) Therefore, in the algorithmic approach for the evaluation of these diseases, the silver stain plays an important role in determining the diagnostic pathway to follow to fully characterize the disorder in question.
In the most severely involved areas, there were double contours of the capillary walls, and even the well-preserved areas showed some mottling with the Jones silver stain (Figure 4).