pulmonary edema, usually delayed for 1-4 hours, occurring in someone exposed to silage, probably due to nitrogen dioxide; can progress to bronchiolitis obliterans.
Farlex Partner Medical Dictionary © Farlex 2012
silo-filler diseaseA toxic gas-induced pneumonitis and bronchiolitis caused by inhalation of nitrogen oxides in freshly filled grain silos, often coupled with asphyxia.
Cough, light headedness, dyspnoea, cyanosis, haemoptysis, choking.
• Collapse and sudden death;
• Acute alveolar damage with pulmonary oedema;
• Early, reversible bronchiolitis obliterans; and
• Late, irreversible bronchiolitis obliterans.
Mycotoxicosis, an allergic reaction.
High-dose corticosteroids may prevent the bronchiolitis obliterans common in the heavily exposed survivors.
Once grains are stored, plant nitrates are fermented by microbes to NO2 and N2O4, peaking 1–5 days after storage; NO2 reaches terminal airways, forming highly irritating nitrous and nitric acids, causing a chemical pneumonitis and massive pulmonary oedema.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
si·lo-fil·ler's lung(sī'lō-fil'ĕrz lŭng)
Pulmonary edema usually delayed for 1-4 hours, occurring in a person exposed to silage; probably produced by nitrogen dioxide; can progress to bronchiolitis obliterans.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012