silicone disease

(redirected from silicone allergy)

silicone disease

A proposed autoimmune condition allegedly linked to leakage of silicone into surrounding breast and/or systemic penetration thereof.
 
Alleged clinical findings
Fatigue, myalgia, arthralgia, synovitis, serositis, sicca syndrome (dry eyes and mouth), dermatitis, alopecia, lymphadenopathy, gastrointestinal symptoms, fever, night sweats and cognitive dysfunction.
 
Diagnosis
Clinical features, history, microscopy, inductively coupled plasma emission spectroscopy.
References in periodicals archive ?
sup][1] The exact pathophysiology of bowel perforation is still a matter of debate; adherence of the tip of the VP catheter to the bowel wall and subsequent local inflammation and erosion, [sup][2] encasing fibrosis around the tube, [sup][3],[4] and silicone allergy leading to a foreign body-like reaction [sup][5] have been regarded as the possible mechanisms of bowel perforation.
Colonic perforation by ventriculoperitoneal shunt tubing: A case of suspected silicone allergy.