DTD is a major cause of thyroid dysfunction; Graves' disease and silent thyroiditis
are usually associated with thyroid hyperfunction, while Hashimoto thyroiditis is typically associated with hypofunction .
The term thyroiditis encompasses several variants including Hashimoto's, subacute, postpartum, drug-induced, suppurative, Riedel's and silent thyroiditis (1).
Silent thyroiditis occasionally can recur and usually requires only symptomatic treatment.
(5) Nakamura et al reported a familial, springtime occurrence of silent thyroiditis
in only those family members who were allergic to Japanese cedar pollen.
Interferon-a-induced hyperthyroidism: a three-stage evolution from silent thyroiditis
towards Graves' disease.
The samples included 41 sera from patients with Graves disease (32 untreated hyperthyroid patients and 9 treated patients) and 42 sera from patients with other thyroid diagnoses, as follows: 13 with Hashimoto thyroiditis, 3 with nodules, 13 with multinodular goiter, 3 with cancer, 2 with silent thyroiditis
, and 8 with no thyroid disease.
Might you have overlooked an episode of silent thyroiditis
? Did you miss a slightly enlarged thyroid?
 (in comparison with amiodarone induced thyrotoxicosis (AIT)): (I) type 1, corresponding to type I amiodarone induced thyrotoxicosis (AIT): (a) GT without TAO and (b) GT with TAO (mild or severe); (II) type 2 destructive thyrotoxicosis, partially analogous to type II AIT: (a) asymptomatic: silent thyroiditis
and (b) symptomatic; and (III) type 3 unknown aetiology, partial analogy to type III AIT--undefined or mixed.
Thyroiditis, toxic nodular goiter, thyrotropin-secreting pituitary tumor, ingestion of thyroxine, silent thyroiditis, and therapeutic doses of iodine are other reported causes of thyrotoxic hypokalemic periodic paralysis (3,10-12).
Silent thyroiditis with thyroid-stimulationblocking antibodies (TSBAb).
The antibodies also appear in autoimmune thyroid diseases such as Graves disease, Hashimoto thyroiditis, silent thyroiditis, and subacute thyroiditis (4-7), and nonthyroid autoimmune disease (6).
A case of progressive systemic sclerosis (PSS) with silent thyroiditis and anti-bovine thyrotropin antibodies.