signet-ring cell carcinoma


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sig·net-·ring cell car·ci·no·ma

a poorly differentiated adenocarcinoma composed of cells with a cytoplasmic droplet of mucus that compresses the nucleus to one side along the cell membrane; arises most frequently in the stomach, occasionally in the large bowel or elsewhere.
References in periodicals archive ?
Signet-ring cell carcinoma of the rectum with tonsillar metastasis: A case report.
Tonsillar metastasis revealing signet-ring cell carcinoma of the rectum.
Tonsillar metastasis of primary signet-ring cell carcinoma of the cecum.
Primary signet-ring cell carcinoma of the uterine cervix with long term follow-up: case report.
10,11] The coexistent signet-ring cell carcinoma and poorly differentiated urothelial cancer in our case may support such hypothesis.
Case reports of signet-ring cell carcinoma originating from different primary sites but also adenocarcinomas of the bladder indicate similar experiences in as much that responses, if encountered, appear to follow 5-FU-based regimens.
Elevated serum carbohydrate antigen 19-9 and CEA has been found to be elevated in signet-ring cell carcinoma in the past.
Primary signet-ring cell carcinoma of the urinary bladder successfully treated with intra-arterial chemotherapy alone.
However, a PAS or PAS-D stain is not specific for the establishment of signet-ring cell carcinoma because some signet-ring cell melanomas may show PAS+ intracellular inclusions (Table).
In yet other studies, mucinous carcinoma has been linked to adverse outcome only when mucinous and signet-ring cell carcinomas have been grouped together and compared with typical adenocarcinoma.
dagger]) By convention, signet-ring cell carcinomas are assigned grade 3 (see later).