castration cells

(redirected from signet ring cells)

cas·tra·tion cells

altered basophilic cells of the anterior lobe of the pituitary that develop following castration; the body of the cell is occupied by a large vacuole that displaces the nucleus to the periphery, giving the cell a resemblance to a signet ring.
Synonym(s): signet ring cells

cas·tra·tion cells

(kas-trā'shŭn selz)
Altered basophilic cells of the anterior lobe of the pituitary that develop following castration; the body of the cell is occupied by a large vacuole that displaces the nucleus to the periphery, giving the cell a resemblance to a signet ring.
Synonym(s): signet ring cells.
References in periodicals archive ?
(14) Morphologically, noncystic adenocarcinomas of the urachus are similar to primary adenocarcinomas of the urinary bladder and can demonstrate a range of histologic subtypes including (1) enterictype adenocarcinoma; (2) mucinous adenocarcinoma, with or without signet ring cells; and (3) adenocarcinoma, not otherwise specified (see below for additional details).
Microscopy showed a focus comprising of signet ring cells suggestive of gastric carcinoma.
Alcian Blue Stained Endoscopic Biopsy showing Signet Ring Cells.
Immunohistochemical staining of the signet ring cells demonstrated these cells to be negative for AE1/AE3, CD138, or Kreyberg staining while being positive for S-100 staining (Figures 1(e) and 1(f)); the immunoprofile was most consistent with atrophic adipocytes rather than signet ring cell carcinoma.
Young, "Primary ovarian mucinous tumors with signet ring cells: Report of 3 cases with discussion of so-called primary krukenberg tumor," The American Journal of Surgical Pathology, vol.
Signet ring cells are more frequently seen focally within otherwise high-grade prostate cancers and should be considered as part of the Gleason scoring.
Histopathologic examination revealed that the mass was composed of pleomorphic cells that varied in shape, identified as cuboidal, columnar, and large round signet ring cells. Neoplastic cells had areas of vacuolated cytoplasm with a small amount of mucous present.
Cytologic criteria were Nuclear morphology (Large nuclei, Anisonucleosis, Hyperchromatic nuclei, Vesicular nuclei, Chromatin clumping, Prominent nucleoli, Multiple nucleoli), and Cellular morphology (Comet cells, Signet ring cells, Vacuolar cytoplasm, Granular cytoplasm, Apocrine cells, Ractive ductal cells, Squamous cells).
Mucinous and signet ring cells were more often identified (p=0.041) in the gene product-deficient group (23.5% v.
Myxoid liposarcomas are as common as the welldifferentiated type; they are composed of proliferating lipoblasts at varying stages of differentiation, signet ring cells, a plexiform capillary pattern, and a myxoid matrix with nonsulfated glycosaminoglycans.