signal peptide


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signal peptide

a short sequence that directs PROTEINS to, and across, MEMBRANES. see LEADER PEPTIDE.
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In addition, we predicted the duck LEAP-2 gene structure as a signal peptide, pro-peptide, and mature peptide based on the LEAP-2 sequences of mammals and other avian species (Figure 1).
In our sequences, it is possible to observe the translated ORF containing a partial signal peptide (20 aa), followed by an entire B chain (37 aa), a C chain (63 aa), and a partial section of A chain (31-33 aa), which are characteristic domains of the insulin-like peptide (Fig.
In both cases, peptide hormone genes are initially translated as biologically inactive prepropeptides, followed by removal of the N-terminal signal peptide by a signal peptidase to afford a propeptides.
The putative signal peptide sequences were localized to the acidic spacer peptide and were highly identical in structure.
• Secretion with LipA or YocH signal peptide up to 9-fold increased
Pairwise alignment reveals that pneumolysin do not have the N-terminus signal peptide sequence which is present in the template i.e.
Furthermore LK2 and LK5 contained signal peptide, low expression of the enzyme might be due to some of the enzyme might be secreted.
This OLR1 is a 270-residue protein in bovine carrying 52-amino acid-long signal peptide. A Pro-His substitution was noted at 17th position, which enhanced OLR1 protein hydrophilicity for enhanced attachments.
Moreover, a recent study reported that the BNP signal peptide derived from preproBNP also circulates in human blood and represents a potential biomarker for cardiac ischemia and myocardial infarction (8).
Previous studies have demonstrated an effect of a T1128C single nucleotide polymorphism (Leu7Pro) in the signal peptide of NPY (prepro-NPY) on parameters of lipid metabolism, glucose control, and even vascular disease: The 7Pro substitution has been associated with higher total [17] and LDL cholesterol levels [18], increased blood pressure [19], increased risk for type 2 diabetes [20], the frequency of the metabolic syndrome [21, 22], and increased vascular disease [19, 23-27].
For this, we provided a multidrug-resistant variant of HIV-1 RT (RT1.14) [16], complemented for safety sake, with mutations inhibiting polymerase and RNase H activity, with a leader signal peptide (Ld) of the nonstructural protein 1 of tick-borne encephalitis virus (NS1 of TBEV).

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