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the development of sickle cells in the blood.
sickling test a method of demonstrationg hemoglobin S and the sickling phenomenon in erythrocytes, performed by reducing the oxygen concentration to which the erythrocytes are exposed.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
sickle cell testA qualitative screening test for sickling haemoglobins, especially HbS. In the SCT, sodium metabisulfite or sodium dithionate is used to desolubilise haemoglobin S to the crystallised deoxygenated form, which causes the abnormal RBCs to sickle, as detected by light microscopy.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
A test that measures the propensity of red blood cells to sickle under conditions of reduced oxygen tension. The test may be performed by adding sodium metabisulfite to a drop of blood and examining the blood smear microscopically. Hemoglobin electrophoresis is an alternative test for sickle cell disease.
Medical Dictionary, © 2009 Farlex and Partners
sickling testThe observation of a blood film, mixed with a solution of sodium metabisulphite, under the microscope. If haemoglobin S is present the red cells will assume a sickle shape within 20 minutes. See also SICKLE CELL ANAEMIA.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005