sickle

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Related to sickled: sickle cell, sicklied

sickle

(sĭk′əl)
v. sick·led, sick·ling, sick·les
v.tr.
To deform (a red blood cell) into an abnormal crescent shape.
v.intr.
To assume an abnormal crescent shape. Used of red blood cells.
adj.
Shaped like the blade of a sickle; crescent-shaped: a sickle moon.

sickle (sik´əl),

Patient discussion about sickle

Q. Please precribe for me the possible medicine (treatment) for sickle cells. Secondly, my boy lost hearing at 4 1- I need to know how sickle cells can be treated. 2- My boy just surprisingly lost his abillity to hear anything at the age of 4.

A. wow...you are going through some hard times...it's the hardest thing in the world seeing your children in pain. loosing his hearing could be caused by clots that were formed and destroyed the ear nerve. but it's unlikely it happened in both ears...so i would check it out. and about treatment- there are a variety of treatments, so i found a web site with them all. and even some that are still in research: http://www.nhlbi.nih.gov/health/dci/Diseases/Sca/SCA_Treatments.html

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References in periodicals archive ?
To manage his disease, Nazaire recently underwent apheresis, a transfusion procedure that removed and replaced some of his red blood cells in an attempt to decrease the proportion of sickled ones.
Rapid reversal of multiple organ failure with simple and/or exchange transfusion support the theory of microvascular occlusion by sickled cells.
Because sickled red cells are often removed from the blood by the spleen, the number of red cells in the body is constantly reduced, producing anaemia.
Occlusion of vessels is thought to be the result of complex processes including blockage by sickled cells, vascular intimal hyperplasia, thrombosis, and/or failure of compensatory vasodilatation (Francis a Johnson, 1991).
This happens when blood vessles in the brain are blocked by sickled red blood cells.
The sickled cells, which become stiff and sticky, clog small blood vessels, depriving tissue from receiving an adequate blood supply.
The blockage of blood flow caused by sickled cells also causes damage to most organs including the spleen, kidneys and liver.
Also, because the sickled red cells die much faster than normal red cells and cannot be replaced quickly, sufferers are chronically short of red blood cells, giving rise to anemia.
Abnormally shaped, or sickled, red blood cells get trapped in blood vessels in the lungs of people with the syndrome.