sickle cell trait


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trait

 [trāt]
1. any genetically determined condition; also, the condition prevailing in the heterozygous state of a recessive disorder, as the sickle cell trait.
2. a distinctive behavior pattern.
sickle cell trait the condition, usually asymptomatic, of being heterozygous for hemoglobin S; see also sickle cell.

sick·le cell trait

the heterozygous state of the gene for hemoglobin S in sickle cell anemia.

sickle cell trait

n.
A hereditary condition, usually harmless and without symptoms, in which an individual carries only one mutated hemoglobin gene for sickle cell anemia. The sickle cell trait confers resistance to some forms of fatal malaria.

sickle cell trait

Heterozygosity for HbS seen in 8% of US blacks, up to 30% of African populations Clinical No anemia, normal growth, development, lifespan, slight ↑ in sudden unexplained death; hematuria, splenic infarction. See Sickle cell disease.
References in periodicals archive ?
With sickle cell trait, intense exertion can cause sickle-shaped cells to accumulate and create logjams in the blood vessels.
The total erythrocytes was significantly decreased in sickle cell disease when compared with normal and sickle cell trait, also the haemoglobin concentration and packed cell volume were significantly lower than that of normal individuals and sickle cell trait patients, respectively, indicated to anaemia in sickle cell disease patients, this results agreed with Losek et al, [7] whom observed anaemia significantly more often in patients with sickle cell disease compared with sickle cell trait at all ages 3 months and older.
Naik et al., "Sickle cell trait and the risk of ESRD in blacks," Journal of the American Society of Nephrology, vol.
A 26-year-old African American male with a history of congenital cerebral palsy, sickle cell trait, and intellectual disability presented with abdominal pain that started four hours prior to the hospital visit.
She realised that regular consumption of cassava - more common in the Southeast than the Northwest - could, by working as an anti-malarial drug, affect the prevalence of the sickle cell trait, by making it less advantageous.
Bilateral anterior and lateral compartment syndromes in a patient with sickle cell trait. Case report and review of the literature.
(4) first described RMC on the basis of their observation of 34 patients with sickle cell trait. RMC is a very rare subtype of renal cell carcinoma which usually occurs in children and young adults with sickle cell trait and disease.
The investigators examined a possible link between Hb[A.sub.1c] and sickle cell trait, which affects hemoglobin even though it doesn't confer sickle cell disease, by analyzing data from two cohort studies involving African American adults.
Nagel, "Plasma lipids in Iranians with sickle cell disease: hypocholesterolemia in sickle cell anemia and increase of HDL-cholesterol in sickle cell trait," Clinica Chimica Acta, vol.
Roetker et al., "Prospective study of sickle cell trait and venous thromboembolism incidence," Journal of Thrombosis and Haemostasis, vol.
The patient himself reported having sickle cell trait and getting exchange transfusions as a child.
Sickle cell disease affects about 1 in every 365 black births, with 1 in 13 black babies born with sickle cell trait.