sickle cell retinopathy

sick·le cell ret·i·nop·a·thy

a condition marked by dilation and tortuosity of retinal veins and by microaneurysms and retinal hemorrhages; advanced stages may show neovascularization, vitreous hemorrhage, or retinal detachment.

proliferative sickle retinopathy

An ophthalmopathy which is the most severe ocular change in sickle cell disease, and linked to local hypoxia due to sludging of sickled cells within vessels. It is characterised by microaneurysms, tortuous retinal veins, haemorrhage, exudates, neovascularisation and, if extreme, retinal detachment.

Stages
▪ Stage I—Peripheral arteriolar occlusion, usually between equator and ora serrata.
▪ Stage II—Peripheral arteriolar-venular anastomoses, usually in temporal quadrant.
▪ Stage III—Neovascularisation, fibrous proliferatrion, vascular leakage, giving rise to seafan and sunburst pattern.
▪ Stage IV—Vitreous haemorrhage, commonly arising from neovascularisation.
▪ Stage V—Retinal detachment.

sick·le cell ret·i·nop·a·thy

(sik'ĕl sel ret'i-nop'ă-thē)
Ocular disorder marked by dilation and tortuosity of retinal veins, and by microaneurysms and retinal hemorrhages; advanced stages may show neovascularization, vitreous hemorrhage, or retinal detachment.
References in periodicals archive ?
Sickle cell retinopathy and other chronic complications of sickle cell anemia: A clinical study of 84 Sub-Saharan African cases (Cameroon).
At the Ophthalmology department, 16 (18.6%) out of the 86 patients seen in 2014 were diagnosed with sickle cell retinopathy. Twenty-eight (51.9%) of 54 patients seen by the urologists in 2014 had priapism.
For example, sickle cell retinopathy, pseudoexfoliation glaucoma, rubeosis iridis, optic neuritis, herpes zoster ophthalmicus, phthisis, retinopathy of prematurity and several nerve palsies.
Posterior segment--non-proliferative sickle cell retinopathy:
Posterior segment--proliferative sickle cell retinopathy:
These changes can be broadly split into two groups: non-proliferative sickle cell retinopathy (NPSR); and proliferative sickle cell retinopathy (PSR).
Idiopathic juxtafoveolar retinal telangiectasis (IRT) must be differentiated from other systemic and ocular diseases associated with telangiectasias like diabetic retinopathy, retinal vascular occlusions, Eale's disease, retinopathy of prematurity, or sickle cell retinopathy. There is an association with parafoveal telangiectasia and abnormal glucose tolerance tests.
Features of sickle cell retinopathy include all of the following EXCEPT: