sicca complex

sic·ca com·plex

dryness of the mucous membranes, as of the eyes and mouth, in the absence of a connective tissue disease such as rheumatoid arthritis.

sicca complex

The constellation of symptoms related to generalised mucosal drying, which is most often associated with Sjögren syndrome but may occur in amyloidosis, haemochromatosis, hyperlipoproteinaemia types IV and V, sarcoidosis, vitamin C and/or A deficiency, scleroderma, and other connective tissue diseases.

Targeted tissues
• Eyes—xeroconjunctivitis due to decreased tears; thick, “ropy” secretions on the inner canthus; foreign body (tired, itchy, sandy) sensation; and decreased visual acuity. 
• Mouth—xerostomia with decreased salivation due to lymphocyte infiltration and duct obstruction, with soreness, adhesion of food to mucosa, “dry cracker” sign, angular cheilitis, fissuring of the tongue, and acceleration of caries.

sicca complex

Symptoms related to generalized mucosal drying, affecting Eyes–xeroconjunctivitis due to ↓ tears, thick, 'ropy' secretions on the inner canthus, foreign body–tired, itchy, sandy sensation, ↓ visual acuity Mouth–xerostomia with ↓ salivation due to lymphocyte infiltration and duct obstruction, with soreness, adhesion of food to mucosa, 'cracker' sign, angular cheilitis, lingual fissuring, acceleration of caries. See Dry eye, Dry mouth.

sic·ca com·plex

(sik'ă kom'pleks)
Dryness of the mucous membranes, as of the eyes and mouth, in the absence of a connective tissue disease such as rheumatoid arthritis.

sic·ca com·plex

(sik'ă kom'pleks)
Dryness of mucous membranes, as of eyes and mouth, in the absence of a connective tissue disease.
References in periodicals archive ?
Objective: To determine the frequency of sicca complex, Sjogren's Syndrome (SS) and Fibromyalgia (FM) in patients with Irritable Bowel Syndrome (IBS).
After examination for objective evidence of sicca complex by Schirmer test, TBUT and Ocular Staining Score (OSS), serological tests were performed.
7 Also sicca complex can be seen in 33% of IBS patients.
Dyck, "Peripheral neuropathy associated with sicca complex," Neurology, vol.
Members of both groups were surveyed about morning stiffness at joints, chronic pain, local pain, reflected pain, subjective swelling history at joints, non-refreshing sleep, paresthesia, fatigue, female urethral syndrome, Raynaud phenomenon, distress, headache, dysmenorrhea, irritable bowel syndrome, depression, allergic rhinitis, and sicca complex.
Symptoms and findings in patient and control groups Patients Controls (n=68) (n=40) n % n % P Morning stiffness in joints 46 67.6 2 5 <0.001 Chronic pain 68 100 8 20 <0.001 Local pain 55 80.8 27 67.5 0.162 Reflected pain 44 64.7 15 37.5 0.009 Subjective swelling history at joints 50 73.5 3 7.5 <0.001 Non-refreshing sleep 64 94.1 7 17.5 <0.001 Paresthesia 55 80.8 8 20 <0.001 Fatigue 67 98.5 25 62.5 <0.001 Woman urethral syndrome 20 29.4 6 15 0.107 Raynaud's phenomenon 0 0 1 2.5 0.37 Distress 62 91.1 14 35 <0.001 Headache 51 75 10 25 <0.001 Dysmenorrhea 26 38.2 7 17.5 0.031 Irritable bowel syndrome 42 61.7 14 35 0.01 Depression 55 80.8 10 25 <0.001 Allergic rhinitis 6 8.8 2 5 0.707 Sicca complex 11 16.1 2 5 0.126 * p < 0.05.
The hallmark of Sjogren's syndrome is the sicca complex of xerostomia and keratoconjunctivitis.
Neuropathy is also associated with Sjogren syndrome, and peripheral neuropathy was more commonly reported in RA patients with Sjogren syndrome or sicca complex (22).