sialyltransferase


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sialyltransferase

(1) N-acetyllactosaminide alpha-2,3-sialyltransferase, EC 2.4.99.6.  
(2) (alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-d-galactosaminide alpha-2,6-sialyltransferase, EC 2.4.99.7. 
(3) Neolactotetraosylceramide alpha-2,3-sialyltransferase, EC 2.4.99.10.
References in periodicals archive ?
Last, recent studies revealed that some non-HLA genes, such as sialyltransferase ST8SIA2 , the complement regulator CSMD1 , and the integrin ITGA1 , may also be associated with cardiac manifestations of NLS.
Enzymatic characterization of a Gal [beta] 1 to 3(4)GlcNAc [alpha] 2 to 3 sialyltransferase and a Gal [beta] 1 to 4GlcNAc [alpha] 2 to 6 sialyltransferase from rat liver.
Maternal low-level lead exposure reduces the expression of PSA-NCAM and the activity of sialyltransferase in the hippocampi of neonatal rat pups.
The 17 chapters explore simple and complex carbohydrates and glycoconjugates; methods of structural analysis of glycosaminoglycans, applications of these methods for identification of lysosomal storage diseases, and participation in the development of Lyme disease; the role of viral envelope protein glycosylation in the pathogenesis of influenza A virus; the application of lectin histochemistry in the diagnosis of lysosomal storage diseases; computational approaches for studying carbohydrate-lectin interactions in infection; the pathogenic effects of altered sialylation of specific glycoconjugates in genetic diseases; sialyltransferase regulation of cancer-associated O-glycans; and the history of pectin study, chemistry, and medicinal uses of pectin.
The B lymphocyte adhesion molecule CD22 interacts with leukocyte common antigen CD45RO on T cells and alpha 2-6 sialyltransferase, CD75, on B cells.
After injury, regenerating hepatocytes have increased sialyltransferase activity and synthesize hypersialylated proteins (e.
Thus CHO cell lines appear to express the [alpha]2,3-sialyltransferase but not a functional [alpha]2,6 sialyltransferase (27).
In the last years, the search for efficient sialyltransferase inhibitors was revived.
The equivalent gene in serogroups W and Y is also a sialyltransferase, but it also has a glycosyltransferase function and is distinct from the serogroups B and C genes.
Similarly, increases in the expression of both FucT-IV and the sialyltransferase ST3Gal II are observed in human colorectal cancer biopsy specimens compared with adjacent noncancerous tissue (54).
The manipulation of cell-surface carbohydrate expression by the sialyltransferase gene may provide a new therapeutic approach for treatment of malignant tumor cells (20).