sialoprotein

si·al·o·pro·tein

(si-yăl-ō'prō-tēn'),
A protein produced by the salivary glands and thereby usually present in saliva.
See also: protein.
Synonym(s): salivary protein
[sialo + protein]

si·al·o·pro·tein

(sīă-lō-prōtēn)
Protein produced by salivary glands and thereby usually present in saliva.
References in periodicals archive ?
Expression of bone sialoprotein mRNA during bone formation and resorption induced by colchicine in rat tibial bone marrow cavity.
According to recent studies, in contrast to our previous knowledge, vascular calcification is an actively regulated process and human vascular smooth muscle cells can express osteoblastic transcription factors (100,101) and bone-regulating proteins such as matrix Gla protein, osteopontin, osteocalcin, collagen 1, osteonectin, bone morphogenic proteins, alkaline phosphatase, and bone sialoprotein. The calcification can occur either in an intimal or in a medial layer of arteries.
(3) In addition, a mature OB also secretes high levels of osteopontin, osteonectin, bone sialoprotein, and type I collagen.
NCAM: neural cell adhesion molecule; MAP2: microtubule-associated protein 2; NeuN: neuron-specific nuclear protein; Fit-I: VEGF receptor 1; KDR: VEGF receptor 2; CD34: cluster of differentiation 34; ICAM-I: intercellular cell adhesion molecule-1; vWF: von Willebrand factor, DSP: dentin sialoprotein, DMP1: dentin matrix acidic phosphoprotein 1, BSP: bone sialoprotein, OCN: osteocalcin, MyoD1: myoblast determination protein 1; MHC: major histocompatibility complex; PCR: polymerase chain reaction; FC: flow cytometry; ICC: immunocytochemical.
Decreased FOX1 suppresses osteoblastogenesis by decreasing osterix and type 1 collagen protein levels but does not affect levels of Runx2 and Bsp (bone sialoprotein) [40].
PCR was performed using a real-time PCR kit (SYBR Premix Ex Taq II, TaKaRa) to detect osteopontin (OPN), osteocalcin (OC), bone sialoprotein (BSP), Runx2, and type I collagen (COL-I) mRNA on a Light Cycler 480 II (Roche, Germany).
Cathepsin G, for example, is able to cleave leukosialin (CD43), the predominant cell surface sialoprotein of leukocytes, and releases its extracellular domain [59].
Monolayers were fixed with paraformaldehyde (4%), permeabilized, and incubated with one of two primary antibodies: first, polyclonal anti-DSPP (Abcam, Cambridge, MA, USA), which is specific to the DSPP N-terminus corresponding to the natural cleavage fragment dentin sialoprotein (DSP); second, anti-DMP-1 (Sigma-Aldrich).
In their differentiation assays, the authors found that the osteoblastic differentiation markers, alkaline phosphatase (ALP) and osteopontin (OPN), were upregulated in vibrated cells while the osteoblastic markers, OC and bone sialoprotein (BSP), were unaffected.
Elevated serum bone sialoprotein and osteopontin in colon, breast, prostate, and lung cancer.
To verify osteogenic differentiation of AD-MSCs after 21 days of cultivation in osteogenic medium, we performed relative quantification of gene transcripts of osterix (OSX), bone sialoprotein (BSP), and osteocalcin (OC) by real time RT-PCR using the [2.sup.-delta delta CT] method.
Despite weaker histologic differentiation, SHED cells have bone tissue-specific markers on their surfaces, such as bone sialoproteins and specific dentin marker (dentin sialoprotein, DSP).