HIV associated salivary gland disease, hepatitis C virus associated sialadenitis, drug associated salivary gland disease, granulomatous sialadenitis, nonspecific reactive changes, necrotizing sialometaplasia
, Sjogren's syndrome and Mikulicz syndrome are other non- neoplastic salivary gland lesions.
The pathological differential diagnosis of MEC of the lacrimal gland may include inverted duct papillomas, cheilitis glandularis, necrotizing sialometaplasia
, cystadenoma, cystadenocarcinoma, sebaceous carcinoma and other clear cell tumours, adenosquamous carcinoma, metastatic squamous cell carcinoma, and rarely pleomorphic adenoma.
When it is involving the oral cavity, the most commonly involved sites are tongue, palate, buccal mucosa, gingiva, and pharynx and the differential diagnoses should include squamous cell carcinoma, hematologic malignancy, tuberculosis, other deep fungal infections, oral lesions of Crohn's disease, necrotizing sialometaplasia
of the palate, and chronic traumatic ulcers.
Similarly, mucoepidermoid carcinoma can have varied morphologic appearance, whereby the differential diagnosis may include necrotizing sialometaplasia
, inverted papilloma, cystadenoma, and various carcinomas with squamous or clear cell features.
is a condition which mostly arises from palatal minor salivary glands.
We report a rare case of necrotizing sialometaplasia
of the right lateral nasopharynx with extension into the right parapharyngeal space in a 39-year-old man.
Systemic granulomatous disease and sialometaplasia
in a dog with Bartonella infection.
The differential diagnosis precluded minor salivary gland tumors, necrotizing sialometaplasia
& ulcers secondary to systemic diseases like HIV, diabetes & blood dyscrasias.
The differential diagnosis of a palatal tumor should include abscess, adenomatous hyperplasia, necrotizing sialometaplasia
, and paranasal sinus tumors.
of the lip simulating squamous cell carcinoma.
Included in the histologic differential diagnosis of salivary gland SMEC are sclerosing polycystic adenosis, chronic sclerosing sialadenitis, low-grade cystadenocarcinoma, and necrotizing sialometaplasia
. (7, 8)
To the Editor.--I read with great interest the recent case reported by Carlson (1) on a bulimic patient presenting with necrotizing sialometaplasia
(NSM) in the hard palate.