Similarly, mucoepidermoid carcinoma can have varied morphologic appearance, whereby the differential diagnosis may include necrotizing sialometaplasia
, inverted papilloma, cystadenoma, and various carcinomas with squamous or clear cell features.
is a condition which mostly arises from palatal minor salivary glands.
We report a rare case of necrotizing sialometaplasia
of the right lateral nasopharynx with extension into the right parapharyngeal space in a 39-year-old man.
The differential diagnosis precluded minor salivary gland tumors, necrotizing sialometaplasia
& ulcers secondary to systemic diseases like HIV, diabetes & blood dyscrasias.
Systemic granulomatous disease and sialometaplasia
in a dog with Bartonella infection.
The differential diagnosis of a palatal tumor should include abscess, adenomatous hyperplasia, necrotizing sialometaplasia
, and paranasal sinus tumors.
Pseudocarcinomatous hyperplasias of the skin (97,98) (Figure 6, A and B), acroangiodermatitis, (99) myositis ossificans (100,101) (Figure 7, A through D), atypical (ischemic) decubital fibroplasia, (102) tumefactive synovial chondrometaplasia, (103) necrotizing sialometaplasia
, (104) gliosis, (105) nephrogenic urothelial metaplasia (106) (Figure 8, A and B), inflammatory polyps of the anorectal region, (107) colitis cystica profunda, (108) florid reactive mesothelial proliferations (109) (Figure 9, A and B), tumorlike chronic pancreatitis, (110) and radiotherapy-induced tissue reactions (111) (Figure 10, A and B) are all examples of this category.
Included in the histologic differential diagnosis of salivary gland SMEC are sclerosing polycystic adenosis, chronic sclerosing sialadenitis, low-grade cystadenocarcinoma, and necrotizing sialometaplasia
I read with great interest the recent case reported by Carlson (1) on a bulimic patient presenting with necrotizing sialometaplasia
(NSM) in the hard palate.
(NSM) is a benign, self-healing lesion of salivary glands, which represents less than 1% of biopsied oral lesions.
is a benign, spontaneously healing inflammatory condition.
MECs must be distinguished from necrotizing sialometaplasia
, chronic sialadenitis, cystadenoma, cystadenocarcinoma, squamous cell carcinoma, epithelial-myoepithelial carcinoma, clear cell carcinoma (not otherwise specified), and metastatic tumors.