Earlier, majority of scientists concluded that some viruses depend on sialic acid
to infect the body, while others were thought to cause infection independent of sialic acid
(2009) Sialic acids
. In Essentials of Glycobiology (eds.
Diabetes mellitus is associated with an increase in sialic acid
concentration along with other complications.
This is because sperms are naturally coated with sialic acid
and the innate immune system uses sialic acid
to distinguish human cells from invaders.
The chemistry and biology of sialic acids
and related substances.
The neuraminidase of influenza viruses is responsible for the cleaving sialic acids
from receptors, thus preventing self-aggregation and enabling the release of virus during budding from host cells (Palese et al., 1974).
2-keto-3-deoxy-D-glycero-D-galac to-nononic acid, a member of the sialic acid
family has distinctive properties such as insensitivity to various sialidases and the association of N-acetyl group with the hydroxyl group of NeuAc (N acetylneuraminic acid) has been shown to be related to human cancers (2-3).
(Sias) are a large family of nine carbon monosaccharide sugars.
 Since sialic acids
are major constituents of glycoproteins and glycolipids, this study is concerned with TSA and/or LBSA levels.
The thiobarbituric acid assay of sialic acids
. J Biol Chem 1959; 234: 1971-5.
can occur as terminal residues at antennae.
acetylesterase (SIAE, Ensembl: ENSG00000 110013) is an enzyme that regulates the cell surface acetylation of sialic acids