Earlier, majority of scientists concluded that some viruses depend on
sialic acid to infect the body, while others were thought to cause infection independent of
sialic acid.
(2009)
Sialic acids. In Essentials of Glycobiology (eds.
Diabetes mellitus is associated with an increase in
sialic acid concentration along with other complications.
This is because sperms are naturally coated with
sialic acid and the innate immune system uses
sialic acid to distinguish human cells from invaders.
The chemistry and biology of
sialic acids and related substances.
The neuraminidase of influenza viruses is responsible for the cleaving
sialic acids from receptors, thus preventing self-aggregation and enabling the release of virus during budding from host cells (Palese et al., 1974).
2-keto-3-deoxy-D-glycero-D-galac to-nononic acid, a member of the
sialic acid family has distinctive properties such as insensitivity to various sialidases and the association of N-acetyl group with the hydroxyl group of NeuAc (N acetylneuraminic acid) has been shown to be related to human cancers (2-3).
Sialic acids (Sias) are a large family of nine carbon monosaccharide sugars.
[5] Since
sialic acids are major constituents of glycoproteins and glycolipids, this study is concerned with TSA and/or LBSA levels.
The thiobarbituric acid assay of
sialic acids. J Biol Chem 1959; 234: 1971-5.
Sialic acids can occur as terminal residues at antennae.
Sialic acid acetylesterase (SIAE, Ensembl: ENSG00000 110013) is an enzyme that regulates the cell surface acetylation of
sialic acids.
