short tandem repeat

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Related to short tandem repeat: Single nucleotide polymorphism, RFLP


A highly polymorphic segment of DNA composed of repetitive stretches of short sequences of 2–6 base pairs of DNA, which serve as genetic markers to track inheritance in families. Microsatellites include dinucleotides, trinucleotides and tetranucleotides, repeated in tandem arrays throughout a genome. The human genome has 50–100,000 microsatellite loci.

short tandem repeat (STR)

short repetitive DNA sequence. The repeat unit is generally 1–13 NUCLEOTIDES in length and the number of repeats varies in different individuals, usually from 5 to 20. The POLYMERASE CHAIN REACTION (PCR) can be used to determine the number of repeats at a LOCUS, by using PRIMERS that anneal either side of the STR, and analysing the size of the resulting PCR product after amplification. Useful for identification of individuals by DNA FINGERPRINTING.Also called microsatellite DNA
References in periodicals archive ?
leprae in 10 polymorphic loci short tandem repeats (STRs) was investigated in clinical specimens obtained from leprosy patients from geographically defined areas.
Twelve short tandem repeat loci Y chromosome haplotypes: Genetic analysis of populations residing in North America, Forensic Science International (2005) 150:1-15.
DNA donors were informed of the scope of the study prior to their providing written consent for analysis and comparisons of their Y chromosome short tandem repeat (Y-STR) haplotypes.
Genotype Profiles for Six Population Groups at the 13 CODIS Short Tandem Repeat Core Loci and Other PCRBBased Loci.
We are seeking to engage with suppliers of DNA polymerase which will be used in techniques that include but are not limited to Polymerase Chain Reaction (PCR) Sequence Specific Oligonucleotide Probes (SSOP) (Luminex ()), Next Generation Sequencing, Real Time PCR, PCR Single Specific Primer (SSP), Sanger sequencing, Short Tandem Repeat (STR) profiling.
Molecular genotyping of hydatidiform moles: analytic validation of a multiplex short tandem repeat assay.
focused on identification of male surnames from Y chromosome short tandem repeat (Y-STR) [2] genotypes (2) (Fig.
Chimerism analysis using polymerase chain reaction (PCR)-based amplification of short tandem repeat (STR) markers has grown to be the most widely used tool for analyzing stem cell engraftment over fluorescent/ns/fu hybridization (FISH) and other cytological methods.
Cats are fastidious groomers, and shed fur can have sufficient genetic material for trace forensic studies, allowing potential analysis of both standard short tandem repeat (STR) and mitochondrial DNA regions," according to researchers.
Short tandem repeat loci and the primer pairs (forward and reverse) required for PCR amplification and sequencing Locus (Zhang, Forward Primer Budiawan et al.
The isolated genomic DNA is used to identify individuals based on their Short Tandem Repeat (STR) profile.
The quality of the DNA obtained from stamps with nexttec columns was compared with that from a silica-based system by short tandem repeat (STR) genotyping using a multiplexed polymerase chain reaction (PCR) system.

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