shiga-like toxins

shiga-like toxins

toxins produced by certain strains of Escherichia coli which disrupt the function of the ribosome. Responsible for the lesions seen in edema disease in pigs, hemolytic uremic syndrome in humans and dogs. Called also verotoxin and vero cytotoxin.
References in periodicals archive ?
Activation of Shiga-like toxins by mouse and human intestinal mucus correlates with virulence of enterohemorrhagic Escherichia coliO91:H21 isolates in orally infected, streptomycin-treated mice.
Of the several virulence factors, Shiga-like toxins Stxl and Stx2 are considered to be the major virulence factors responsible for these clinical symptoms (Nataro and Kaper 1998).
Unfortunately, there is a potential for false-negative test results, particularly in stools that may contain low levels of Shiga-like toxins.
Humoral immune responses to Shiga-like toxins and Escherichia coli O157 lipopolysaccharide in hemolytic-uremic syndrome patients and healthy subjects.
This family of toxins was subsequently also called Shiga-like toxins (SLT), and more recently Shiga toxins (Stx), because of the close relation to the Stx of Shigella dysenteriae type 1.
Stool specimens obtained from all 23 patients during their illness were screened using polymerase chain reaction (PCR) for the genes encoding for Shiga-like toxins (SLTs) I and II(1); of these, 20 (87%) were positive for both SLTs I and II, one (4%) was positive for only SLT II, and two (9%) were negative.
coli that are capable of producing Shiga-like toxins 1 and/or 2.
Enterohemorrhagic Escherichiae coli (EHEC) produce two potent cytotoxins called shiga-like toxins (SLT).
Pseudomonas aeruginosa can cause false-positive identification of verotoxin (Shiga-like toxin) production by a commercial enzyme immune assay system for the detection of Shiga-like toxins (SLTs).