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"We were told it was probably growing pains, but I took him to A&E and, after months of tests, we were told that he had cancer again - this time it was a peripheral nerve sheath tumour in his pelvis.
Lindsey was diagnosed with a Peripheral Neurofibrosarcoma/ Schwannoma Nerve Sheath Tumour.
Abbreviations NFI: Neurofibromatosis type 1 BSC: Breast spindle cell PNST: Peripheral nerve sheath tumours MPNST: Malignant peripheral nerve sheath tumour SCMC: Spindle cell metaplastic carcinoma SMA: Smooth muscle actin IHC: Immunohistochemistry.
A 15-year-old boy with neurofibromatosis type 1 (NF1) was referred to us for central venous catheter insertion, and on ultrasound of the neck, he was found to have extensive involvement of the brachial plexus due to the nerve sheath tumour. Multiple hypoechogenic lesions resembling the internal jugular vein and internal carotid artery were visualised and could be differentiated from the vessels by Doppler ultrasound.
However, dedifferentiated liposarcoma, low grade fibromyxoid sarcoma, deep benign fibrous histiocytoma, malignant peripheral nerve sheath tumour, (Sarcomatoid) mesothelioma, schwannoma, gastrointestinal stroma cell tumour, synovial sarcoma and leiomyoma were negative for STAT6.12
Given the overall rather benign neurogenic differentiation with focal increased cellularity, nuclear atypia, and mitotic activity, the diagnosis of neurofibroma with transition into a low-grade malignant peripheral nerve sheath tumour (MPNST) was made (Figures 5(a) and 5(b)).
Intratesticular benign peripheral nerve sheath tumour in a ferret (Mustela putorius furo).
(5.) Oni OO, A tendon sheath tumour presenting as a trigger finger.
Penile malignant peripheral nerve sheath tumour (schwannoma) in a three-year-old child without evidence of neurofibromatosis.
The 35-year-old diesel engineer learned he had mixed periphery nerve sheath tumour, an aggressive metastatic cancer carried by blood cells.
Malignant peripheral nerve sheath tumour: CT and MRI findings.