severely debilitating illness

severely debilitating illness

Any condition in which there is major irreversible morbidity–eg, AIDS, Alzheimer's disease, blindness, diabetic nephropathy, neurologic degeneration, Parkinson's disease, terminal CA, etc. See Dread disease, Illness, Life-threatening illness.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
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MDD is a severely debilitating illness characterized by sadness and an inability to cope.

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